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       Disease introduction: Liver cancer is one of the high-incidence tumors, and its morbidity and mortality are increasing year by year. Due to the characteristics of region and diet, the common symptoms and clinical manifestations of liver cancer patients are similar to the nature and characteristics of damp pathogens, and symptoms of liver cancer and spleen deficiency appear.

  Experimental animals: nude mice (6-8 weeks)

  Experimental methods: 1. The model mice were fed with senna leaf decoction after one week of adaptive feeding, resulting in a model of spleen deficiency. The model was successful when the mice appeared fatigue, dirty tails, dull hair, and loose stools. After successful spleen deficiency model, a liver cancer model was established. Mouse liver cancer cells were injected into the liver of mice to make liver cancer models. 2.Judge the model by analyzing the liver pathological HE staining.