[Animal modeling] - alcohol induced chronic liver injury model in pigs

  1. Animal modeling materials: miniature pigs, regardless of gender; Medication: Feed containing sufficient nutrients and alcohol (alcohol accounts for 40% of total calories).

  2. The modeling method is to feed miniature pigs with feed containing sufficient nutrients and alcohol for 12-21 months.

  3. Principle of modeling: Liver damage caused by alcohol.

  4. Changes after modeling: The modeling animals showed significant liver cell damage and collagen deposition around the veins, with more extensive central vein and interlobular fibrosis observed over time.