动物造模 zi-bio 2024-02-26 527

　　On the 20th, the reporter learned from the Chinese Academy of Agricultural Sciences that the Innovation Team of Ruminant Nutrition and Feed at the Institute of Feed Research of the institute has revealed the changes in gastric microbiota and antibiotic resistance genes in young goats, providing new ideas for regulating the spread of resistance genes by adjusting the diet of goats. The relevant research was recently published in the international journal Microbiology.

　　There are many microorganisms in the gastrointestinal tract of livestock, most of which carry antibiotic resistance genes. These genes will make bacteria resistant to antibiotics. The research team found that the stomach of young goats is like a "storage room", storing many antibiotic resistance genes.

　　Zhang Naifeng, the corresponding author of the paper and a researcher at the Feed Research Institute of the Chinese Academy of Agricultural Sciences, told Science and Technology Daily that the research team collected stomach samples from goats from birth to 84 days old and analyzed the composition of microorganisms and antibiotic resistance genes in these samples using metagenomic sequencing technology. It was found that as goats grew older, the types of antibiotic resistance genes in their stomachs became fewer and fewer. Moreover, when goats are still drinking breast milk, they have several types of antibiotic resistance genes in their stomachs; But when they start eating solid feed, there is only one type of antibiotic resistance gene left.

　　The research team also found a close relationship between the microorganisms in the goat stomach and antibiotic resistance genes. When the type and quantity of microorganisms change, antibiotic resistance genes also change accordingly. Moreover, the antibiotic resistance genes in the stomachs of goats of different ages also vary. "This means that age and diet are important factors affecting antibiotic resistance genes in goats' stomachs," said Zhang Naifeng.

　　This study provides a new perspective and method for us to understand and control the gut microbiota and antibiotic resistance genes in livestock. By adjusting the diet of goats, it is possible to affect the microbiota and antibiotic resistance genes in their stomachs. For example, goats can be fed with foods beneficial to microorganisms, allowing them to grow more 'good' microorganisms in their stomachs, thereby reducing the number of 'bad' microorganisms and antibiotic resistance genes. In this way, the risk of drug resistance gene transmission can be reduced Zhang Naifeng said.