1. Animal modeling materials: Female guinea pigs, weighing 250-300g; Medication: Stone feed (formula: add 1.5% sucrose, 1% casein, 1% lard, 1% cellulose, 0.02% bile acid, and 0.05% cholesterol to the basic food).
2. Modeling method: Model animals are fed with stone feed. Mold will be formed in 2 months.
3. Principle of modeling: Diet causes animal gallstones.
After 2 months of modeling, 90% of guinea pig gallbladder can produce gallstones mainly composed of bile pigments, which are similar in composition and structure to human gallstones.