Diabetes peripheral neuropathy is one of the common complications of diabetes. at present, the understanding of its pathogenesis is not clear enough, and there is a lack of effective treatment methods. The criteria for the success of modeling and the evaluation method for the recovery of peripheral nerve function are the key to the animal experiment of diabetes peripheral neuropathy, but there is a lack of sorting and analysis of the evaluation methods for the model of diabetes peripheral neuropathy.
Therefore, the author reviewed the data in recent years, summarized and analyzed the evaluation methods of animal models of type 2 diabetes peripheral neuropathy from small nerve fibers and large nerve fibers, and proposed the possible development direction in the future, with a view to providing reference for related research.