动物造模,产后抑郁 zi-bio 2024-03-19 750

　　Postpartum depression refers to a series of depressive symptoms that postpartum women experience from the beginning of childbirth to postpartum, such as sadness, depression, crying, irritability, lack of confidence in life, and in severe cases, even suicidal or infanticide tendencies. The incidence of PPD is related to social psychological factors and biological factors, and the incidence rate is about 10%~15%. Relevant research shows that the proportion of women who have anxiety or depression symptoms in the weeks, months or years after delivery is significantly higher than that in other periods. At least one in ten women will have anxiety or depression symptoms after delivery, and the incidence rate is the highest within one month after delivery. Compared to simple depression, PPD has significant differences in animal models and behavioral evaluations due to the complexity and variability of the disease and the special period of postpartum delivery. This article provides a review of animal models of postpartum depression and their behavioral evaluation methods.