动物造模,白血病,药效评价 zi-bio 2024-10-22 901

　　Leukemia, also known as "blood cancer", is characterized by the malignant and unrestricted proliferation of leukemia cells in the bone marrow and other hematopoietic tissues, infiltrating various tissues and organs throughout the body, producing different symptoms, making patients prone to serious infections or secondary sepsis, causing bleeding, intestinal failure, hyperuricemia, and other serious threats to their lives. Therefore, research on leukemia treatment is crucial. The use of experimental animals for various disease and drug efficacy experiments is an important aspect of the development of the pharmaceutical field. For the study of leukemia, mice are similar to humans in biology, genetics, hematopoietic system, and other aspects, making them an ideal animal leukemia model. This article provides a review of commonly used mouse leukemia models in domestic and foreign research over the past five years