[Animal modeling] - sulfur dioxide induced chronic bronchitis model in mice

  1. Animal modeling material: Monkey; Medication: SO2; Equipment: fumigation box.

  2. Modeling method: Model animals inhale 5-8ml/10L of SO2 air for 2 hours a day, 5 times a week, for 65 days.

  3. The principle of modeling is to establish a chronic bronchitis model by inhaling SO2 to cause tracheal injury and inflammation in animals.

  4. Changes after modeling: After 50 days of modeling, the animal glands significantly proliferated and chronic bronchitis lesions appeared.