动物造模,药效筛选,肺纤维化 z-bio 2024-06-14 454

　　1. Animal modeling materials: rats, rabbits; Medication: Rabbit antiserum.

　　2. Modeling method: Grind rat lung tissue into homogenate and immunize rabbits with ultrasound treatment to prepare rabbit antiserum. Inject 15mg/ml of immunoglobulin extracted from this serum into the trachea of normal rats.

　　3. Modeling principle: Anti lung antibodies lead to pulmonary fibrosis in animals.

　　4. Changes after modeling: After modeling, the animal's lungs showed inflammation. After 6 months, the inflammatory response almost subsided, and the lungs showed significant fibrosis.