动物造模,药效评价,肺结核 z-bio 2024-06-27 353

　　1. Animal modeling materials: guinea pigs, weighing 350-500g; Drug: Mycobacterium tuberculosis.

　　2. Modeling method: Subcutaneous injection of 0.1mg of bacteria into the armpit or chest of the modeling animal.

　　3. Modeling principle: Mycobacterium tuberculosis infection leads to animal pulmonary tuberculosis.

　　4. Changes after modeling: After modeling, it can cause local ulcers, cheese like changes in nearby lymph nodes, and necrosis in the lungs, liver, and spleen.