动物造模,药效评价,中枢性呕吐模型 z-bio 2024-07-26 449

　　1. Modeling materials animals: dogs, cats, or monkeys; Drug: Apomorphine hydrochloride.

　　2. Modeling method: Subcutaneous injection of 1-1.5mg/kg of apomorphine hydrochloride into model animals.

　　3. Modeling principle: Drug stimulation of the central emetic chemosensory area leads to vomiting in animals.

　　4. After modeling, animals may experience vomiting within 2-3 minutes.