动物造模,药效评价,慢性肝损伤 z-bio 2024-07-29 378

　　1. Modeling material animals: miniature pigs, male or female not limited; Medication: Feed containing sufficient nutrients and alcohol (alcohol accounts for 40% of total calories).

　　2. The modeling method involves feeding miniature pigs with feed containing sufficient nutrients and alcohol for 12-21 months.

　　3. Modeling principle: Liver damage caused by alcohol.

　　4. Changes after modeling: Significant liver cell damage and perivenous collagen deposition were observed in the modeled animals, with more extensive central vein and interlobular fibrosis observed over time.