[Animal modeling - Drug efficacy evaluation] - Anesthetic induced bradycardia model

  1. Modeling material animals: Adult mice weighing 25-40g; Drug: 10% urinary ester; Equipment: Biological function experimental system.

  2. Animal modeling method: Anesthetize animals with 10% urea ester 2mg/g.

  3. Modeling principle: Anesthetics induce arrhythmia and establish animal models.

  4. After modeling, animals may experience transient bradycardia after anesthesia, which usually returns to normal within 10 minutes (450-750 beats per minute).