动物造模,药效评价,肾炎 z-bio 2024-08-12 409

　　1. Modeling material animal: rabbit; Drug: Bovine serum albumin (BSA).

　　2. The modeling method involves injecting 1mg/kg BSA intravenously into rabbits daily. 6 times a week.

　　3. Modeling principle: Induction of animal glomerulonephritis model by heterologous immune complexes.

　　4. Changes after modeling: Urinary protein levels increased 2-3 weeks after injection, and pathological examination showed changes in chronic nephritis in approximately 29% of the models.