动物造模,药效评价,急性肝损伤 z-bio 2024-08-20 259

　　1. Modeling material animals: rats weighing 200-250g, or mice weighing 25-30g, regardless of gender; Medicine: 56 degree Baijiu.

　　2. The model was made by intraperitoneal injection of 56 degree Baijiu. Rats were given 7ml/kg body weight each time (mice were given 16ml/kg body weight each time) twice a day for 2 weeks.

　　3. Modeling principle: Alcohol causes acute liver injury.

　　4. Changes after modeling: The model animals showed hepatic steatosis, mild ballooning, and inflammatory cell infiltration.