z-bio 2025-08-05 2972

　　The 2025 National Natural Review has ended.

　　Recently, the National Natural Science Foundation of China announced the funding results of the 2025 Youth Science Foundation of China (Class A, including continuing funding projects) and Youth Science Foundation of China (Class B). Shandong First Medical University, Shenzhen University, Hubei University and Anhui Agricultural University have successively announced approvals.

　　The details are as follows:

　　The National Natural Science Foundation Youth Science Foundation project supports young scholars who have achieved outstanding results in basic research. They face the world's scientific frontiers and major needs of the country, strengthen the condensation of scientific issues, and independently select research directions to carry out innovative research. The purpose is to promote the growth of young scientific and technological talents and cultivate and create a group of outstanding academic leaders who have entered the world's scientific and technological frontiers.

　　Shandong First Medical University

　　Professor Song Yongfeng of Shandong First Medical University Affiliated Central Hospital, applied for the "Pathology and Intervention Strategy of Lipid Metabolic Disorders" was approved for the Youth Science Foundation Project (Class A) (formerly National Outstanding Youth Science Foundation Project), with a funding amount of 4 million yuan.

　　Professor Song Yongfeng has always insisted on condensing scientific problems from clinical practice, focusing on curing diseases and saving lives and serving the needs of patients, and has condensed and explored scientific problems from medical practice. He has carried out continuous and in-depth research on the current clinical problems such as unclear mechanisms of lipid metabolism disorders, unknown causes, and lack of intervention strategies, and has made important contributions in the field of lipid metabolism disorders. A new concept of cholesterol toxicity was proposed, and the potential harm of excessive cholesterol in various diseases was pointed out, and the role of cholesterol and the traditional understanding of hypercholesterol-related diseases was expanded. The abnormal pituitary hormone levels were clarified as the cause of hypercholesterolemia, proving that pituitary hormones can directly regulate lipid metabolism and clarify molecular mechanisms; a series of important new factors for lipid metabolism regulation were identified and the molecular mechanisms were clarified, and a new strategy to interfere with the prevention and treatment of hypercholesterolemia was proposed, providing potential intervention targets for disease treatment.

　　Song Yongfeng, chief physician, professor, doctoral supervisor, postdoctoral fellow at Yale University, is currently the director of the Central Hospital Affiliated to Shandong First Medical University (Jinan Central Hospital). He also serves as deputy chairman of the Youth Committee of the Endocrinology Branch of the Chinese Medical Association, chairman of the Endocrinologists Branch of the Shandong Medical Association, and member of the Cardiovascular Metabolic Medicine Committee of the National Cardiovascular Disease Expert Committee. He has received funding from the National Natural Science Foundation Youth Science Foundation Project (Class B), and was selected as a special expert for the National Hundred Thousands of Talent Project and Shandong Province Taishan Scholars. He has won honorary titles such as the National Young and Middle-aged Experts with Outstanding Contributions, Outstanding Doctors of Shandong Province, and Top Ten Young Doctors of Shandong Province. He won the China Youth Science and Technology Award and the China Youth Medical Science and Technology Award. As the main person, he won the second prize of the National Science and Technology Progress Award and the first prize of the Shandong Science and Technology Progress Award. In recent years, he has published more than 40 papers in Cell Metabolism (3 articles), Nature Metabolism, Cell Research, Journal of Hepatology, eBioMedicine and other magazines, and many of them have been recommended by F1000 or selected as cover articles. He was invited to publish his opinion article on "lipid metabolism disorders" in the journal Trends in Endocrinology and Metabolism. As a written expert, participate in the formulation of 5 clinical guidelines/expert consensus of the Chinese Medical Association.

　　Hubei University

　　The "Food Safety Sensing Testing" applied by Professor Chen Miaomiao of the School of Chemistry and Chemical Engineering and Food Safety Research Institute of Hubei University was successfully approved for the Youth Science Foundation Project (Class B) (formerly Excellent Youth Science Foundation Project). The project implementation cycle is 3 years and the funding is 2 million yuan.

　　The project moves the prevention and control of peanut aflatoxin pollution forward, focuses on the in-situ monitoring method of toxin-producing flexible sensing infectious infection of peanut aflatoxin, reveals the targets of ARC bacterial agents for the growth, infection and toxin-producing targets of Aspergillus peanut aflatoxin, analyzes the inhibitory mechanism, and aims to provide an important theoretical basis for efficient prevention and control of mycotoxin pollution in grain, oil and food such as peanuts.

　　Chen Miaomiao, female, doctoral, professor at Hubei University, and doctoral supervisor. Outstanding Youth in Hubei Province, Chutian student in Hubei Province.

　　He has long been committed to research on food safety sensing detection methods, and the relevant results have been published in international academic journals such as Chemical Society Reviews, Advanced Functional Materials, Analytical Chemistry, and Food Chemistry. In the past five years, it has undertaken 7 scientific research projects such as the National Natural Science Foundation and the Hubei Provincial Outstanding Youth Fund, and has been authorized 3 patents.

　　Anhui Agricultural University

　　The National Natural Science Foundation Youth Project (Class B) "Research on the Molecular Mechanism of the Natural Disease Resistance Protein L3 in Chili Pepper Recognition of Virus Activation Immunity" hosted by Professor Chen Jing of the School of Plant Protection of Anhui Agricultural University was successfully approved for approval.

　　This project targets the lack of RNA viruses and host disease-resistant resources that seriously endanger pepper production. With the natural disease-resistant protein L3 of pepper as the core, it analyzes molecular mechanisms and explores disease-resistant gene resources. The research results aim to provide theoretical support for establishing a lasting, broad-spectrum antiviral natural immune strategy for important economic crops such as peppers. The project was approved to further consolidate the foundation for the construction of our school's high-level talent team and provide new impetus for the sustainable development of related disciplines.

　　Chen Jing, male, professor (PI) and doctoral supervisor of the Department of Plant Pathology, Anhui Agricultural University, is mainly engaged in plant antiviral immunology research. He has received funding from the National Natural Science Foundation Youth Fund Project (Class B) (2025), and has successively presided over the National Natural Science Foundation Youth Fund Project (Class C) (2023), and the Anhui Provincial Natural Science Foundation Outstanding Youth Fund Project (2023). His paper published as the first author in the official journal of Nature is the first achievement in the field of plant antivirals published by Nature. The research results were selected as one of the top ten scientific and technological progress in Jiangsu Province (the field of modern agriculture), 100 outstanding academic achievements in natural sciences in Jiangsu Province (2024), and recipient of outstanding doctoral thesis in Jiangsu Province (2025). In 2023, he was selected as the top young talents in Anhui Province. As the first/corresponding author, he published papers in internationally renowned journals such as Nature, PLoS Pathogens, Virology journal.

　　Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences

　　Researcher Yang Xueyong from the Institute of Vegetables and Flowers of the Chinese Academy of Agricultural Sciences received Class A funding (formerly good youth) and associate researcher Zhang Jinzhe received Class B funding (formerly good youth).

　　Yang Xueyong, born in 1982, is a researcher at the Institute of Vegetables and Flowers of the Chinese Academy of Agricultural Sciences, doctoral supervisor, and chief scientist of the vegetable functional genome innovation team. It mainly revolves around the biological process of interaction of crop source libraries such as melons in the Cucurbita family, explores and analyzes key variants, genome interactions, and changes with the environment, and creates mutations in a direction to improve crops. It aims to establish a widely applicable methodology, systematically carry out scientific transformation and design of sources, libraries and flows, and achieve a coordinated improvement of crop yield, quality and environmental adaptability. He presided over 6 national, provincial and ministerial projects and projects.

　　As a correspondence/first author, he has published more than 20 SCI papers in journals such as Cell, Nature Plants, and the Plant Cell. He has won the National Youth Excellent Youth and Outstanding Talent Training Program for Agricultural Research. He serves as Secretary-General of the Vegetable Committee of the Chinese Horticulture Society and is an editor of SCI journals such as Horticulture (English version of Journal of Horticulture), Journal of Integrative Agriculture (English version of Chinese Agricultural Sciences), Vegetable Research, etc.

　　Zhang Jinzhe, born in 1989, is an associate researcher at the Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences. He received a bachelor's degree in agriculture from Northwest A&F University in July 2011 and a doctorate in science from Peking University in July 2017. A backbone member of the vegetable functional genome innovation team has been committed to the molecular mechanism of metabolic regulation of tomato flavor substances for a long time. He has discovered several key genes that control the accumulation of flavor substances such as the "sugar brake" gene CDPK27, which has improved the molecular network of flavor regulation, and provided important targets and theoretical guidance for tomato flavor improvement. He has successively presided over the National Natural Science Foundation Youth Project and 1 project in total; authorized 4 national invention patents; won 2 new plant varieties rights; won the Outstanding Science and Technology Innovation Award of the Chinese Academy of Agricultural Sciences in 2020; and was selected as the "Chinese Vegetable Talent at the Institute of Vegetables and Flowers of the Chinese Academy of Agricultural Sciences in 2023. A total of 22 SCI papers have been published, of which 8 papers have been published as the first author or corresponding author in journals such as Nature (2), the Plant Cell, Cell Research, and Molecular Plant.

　　In addition, the funding results have been announced one after another:

　　Zhang Chunzhi from the Institute of Agricultural Genomics, Chinese Academy of Agricultural Sciences received Class A funding (Yuan Jieqing)

　　Liu Yongxin, Institute of Agricultural Genomics, Chinese Academy of Agricultural Sciences, Qing B

　　Shang Lianguang, Institute of Agricultural Genomics, Chinese Academy of Agricultural Sciences, Qing B

　　The lake office has been updated, and Xu Huacheng is added to Class A and Liu Lei is added to Class B.

　　Associate Professor Liu Siyang from the School of Public Health of Sun Yat-sen University (Shenzhen) received funding from the National Natural Youth Science Foundation Class B project

　　Researcher Liu Na from the Vegetable Research Institute of Zhejiang Academy of Agricultural Sciences received Class B funding (formerly Youqing)

　　Researcher Ge Xiaoyang from the Institute of Cotton Research, Chinese Academy of Agricultural Sciences received funding from Class B project (formerly Youqing) and other

　　More information on funding results of universities and research institutions to be updated...