[Animal Modeling] - Animal Model of Qi Deficiency and Blood Stasis Syndrome

  (1) Reproduction method: Adult rats were placed in a water tank with a water temperature of (42 ± 1) ℃ and swam once a day until they naturally sank and were unable to float. They were anesthetized for 10 consecutive days, and their hearts were taken for blood collection and hemodynamic parameters were measured.

  (2) The characteristics of the model forced rats to swim continuously in warm water for 10 days, and the blood rheological tests showed that all indicators were significantly elevated.

  (3) Compared to traditional Chinese medicine, Qi deficiency leads to inability to circulate blood, while poor blood circulation leads to stasis. This method is based on the traditional Chinese medicine theory of "labor consumes qi". Animals are placed in a water tank to swim, causing them to consume qi due to overwork, in order to create a model of Qi deficiency and blood stasis syndrome. The model created by this method needs further evaluation. There have been reports of Qi deficiency syndrome and spleen deficiency syndrome. We believe that the key lies in using appropriate methods and relevant syndrome criteria to determine the attributes of syndrome types.