动物造模,药效评价,刺激法肺气虚证 z-bio 2024-07-29 356

　　(1) Method of replication: Adult rats were stimulated with sulfur dioxide at a dose of (200-250) × 10 ^ -5, for 1 hour per day for 13 days. Wind cold stimulation was performed using cold air at a temperature 5 ℃ lower than the living environment temperature of the rats for 15 minutes per day for 13 days. Wind cold stimulation was performed immediately after the sulfur dioxide stimulation was completed. Detect changes in respiratory rate per minute, endothelin (ET), and other parameters.

　　(2) After modeling, the respiratory rate of rats significantly increased and the plasma ET content significantly increased.

　　(3) The comparative medicine model is based on multiple factors, and the model animals exhibit symptoms of lung qi deficiency syndrome induced by smoking, as well as susceptibility, fatigue, and decreased body surface temperature.