![[Animal modeling] - KK mice with hereditary diabetes](/./uploads/images/default/default.png)
he KK mouse was successfully cultivated in 1957 by Japan\'s Konteng family using the original Japanese mouse (also known as the \"twenty day mouse\"). In 1962, Nakamura reported that KK mice had similar properties to adult obese diabetes, w...
2023-11-27
Select female rat offspring born at the same time period for selective breeding. On the 8th day of age, female rats were subcutaneously injected with testosterone propionate at a dose of 1.25mg/animal in the neck and back, and weaned on the 22nd day ...
2023-11-27
To investigate the effect of astragaloside Ⅱ on the interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...
2023-11-27
Spontaneous hypertensive rats are inbred Wistar rats cultivated by Okamoto and Aoki in 1963 and their control inbred Wistar Kyoto rats. The onset of hypertension in SHR rats is related to an increase in cardiac output. As hypertension progresses, car...
2023-11-23![[Animal Modeling]- Rat Model of High Altitude Erythrocytosis](/./uploads/images/default/default.png)
High altitude polycythemia (referred to as \"hypererythrosis\") is a chronic high altitude disease caused by excessive compensatory proliferation of red blood cells (i.e., excessive proliferation of red blood cells) caused by high altitude ...
2023-11-23![[Animal Modeling ]- Rat Acute Psychological Stress Model](/./uploads/images/default/default.png)
SD rat, 8 weeks old, male. The laboratory temperature is between 18 and 25 ℃, with regular feeding and free diet...
2023-11-23![[Animal Modeling ]- An Animal Model of Cerebral Palsy in Rats](/./uploads/images/default/default.png)
Experimental cerebral palsy animal model in neonatal rats after asphyxia...
2023-11-23![[Animal Modeling] - Establishment of a Tree Shrew Hand, Foot, and Mouth Disease Model](/./uploads/images/default/default.png)
Coxsackie virus A16 (CA16) is commonly considered one of the main pathogens of human hand, foot, and mouth disease. The clinical manifestations of hand, foot, and mouth disease in young children include small vesicles in the hands, feet, and mouth, a...
2023-11-23
Adult mice were used, and methyl thiouracil was mixed with tap water to replace drinking water at a concentration of 0.03%. The model was established for 5 weeks. After the experiment, blood was collected to measure plasma cortisol content, animals w...
2023-11-23
To study the effect of cyclooxygenase inhibitor Fenbid on lumbar disc herniation...
2023-11-22
To establish a mouse model of coronary heart disease-derived intestinal flora by fecal bacteria transplantation and evaluate the model...
2023-11-22![[Animal modeling] - Analysis of Mozart K448 sonata high frequency sound wave on the intervention treatment of mouse depression model](/./uploads/images/default/default.png)
To establish the depression model of C57BL/6 mice and preliminarily explore the effect of high frequency sound wave in Mozart K448 sonata on improving the depression symptoms of C57BL/6 mice...
2023-11-22
To investigate the changes in the content or activity of nuclear factor E2 transcription-related factor 2 (Nrf2) and anti-oxidative stress-related factors in a rat model of traumatic brain injury, and to study the protective effect of curcumin on rat...
2023-11-22![[Animal Modeling] - Rabbit Staphylococcus aureus Infectious Conjunctivitis Model](/./uploads/images/default/default.png)
Inoculation of Staphylococcus aureus into the conjunctiva scratch of the lower eyelid of rabbits causes infectious inflammation of the conjunctiva...
2023-11-22![[Animal modeling] - Effect of long-term high protein diet on liver steatosis and fat accumulation in OVX mice](/./uploads/images/default/default.png)
To investigate the effects of long-term high protein diet on liver and adipose tissue of ovariectomized mice and the role of glucagon like peptide-1 (GLP-1)...
2023-11-21
To investigate the changes of platelet mitochondria after tourniquet ischemia-reperfusion injury, and to provide guidance for the clinical application of tourniquet...
2023-11-21