【Animal Modeling】-Kidney Yang Deficiency Related mRNA Expression and Ultrastructure Observation in the Hypothalamus of Lewis Rats

By observing the gene expression and ultrastructure of hypothalamus related to kidney-yang deficiency in Lewis rats, further study the constitution of Lewis rats with kidney-yang deficiency...

2023-06-16

【Animal Modeling】-Intervention of Fufang Dihuang Granules on Microglia Activation and Neurobehavior in Parkinson\\\\

To investigate the intervention effect of Fufang Dihuang Granules on the activation of nigrostriatal microglia, the expression of inflammatory factors and neurobehavior in different rat models...

2023-06-14

[Animal Modeling]-Establishment of a mouse model of chronic renal insufficiency induced by repeated injection of cisplatin

Establish a C57BL/6 mouse model of chronic kidney disease, study the changes in renal tubular injury index and interstitial fibrosis caused by cisplatin dose, and conduct animal experiments to study the progress of AKI and CKD to provide relevant evi...

2023-06-14

【Animal modeling】-Effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia

To explore the effect and mechanism of Shenqu Xiaoshi Oral Liquid on gastrointestinal motility in functional dyspepsia (FD) mice...

2023-06-14

【Animal Modeling】-Effect of Mac-1 gene deletion on the growth of melanoma

To investigate the effect of Mac-1 deletion on melanoma tumor growth...

2023-06-14

What are the environmental requirements for laboratory animals?

The experimental animal environment refers to a special artificial place where animals are kept in a limited space controlled by humans and grow, reproduce and experiment according to human wishes. The environment outside the breeding room or animal...

2023-06-14

【Animal modeling】-Effect of paeoniflorin on intracellular Ca2+ in rat dorsal root neurons

To establish a method to evaluate the effect of paeoniflorin on the concentration of free Ca2+ in rat dorsal root ganglion neurons...

2023-06-14

Animal Modeling - Study on the Intervention Effect of Bone Marrow Mesenchymal Stem Cells on Rheumatoid Arthritis Mice

To explore the effect of bone marrow mesenchymal stem cells on rheumatoid arthritis and its secondary bone loss using a spontaneous rheumatoid arthritis mouse model...

2023-06-13

This article analyzes the behavioral abnormalities and pathological changes in brain tissue of rats after Trim44 gene knockout using Trim44 conditional knockout, and explores the mechanism of action o

This article aims to analyze the behavioral abnormalities and pathological changes in brain tissue of rats treated with Trim44 gene knockout, and explore the mechanism of action of Trim44 gene in the nervous system...

2023-06-13

【 Animal modeling 】 - The effect of acrylamide exposure during puberty on oxidative damage in mouse lung tissue

To investigate the damage of acrylamide to mouse lung tissue and its possible mechanism...

2023-06-13

[Animal modeling] - Xiaoyusan new formula for repairing cartilage damage and MMP-13 expression in knee Osteoarthritis model rabbits

To study the effect and mechanism of Xiaoyusan new formula on articular cartilage of knee Osteoarthritis rabbits...

2023-06-13

[Animal modeling] - Detection of protein expression profile in liver Histone of mice with alcoholic fatty liver disease and exploration of the intervention mechanism of Resveratrol

To analyze the changes of protein expression profile in liver Histone of mice with alcoholic fatty liver disease and the intervention effect of Resveratrol by Proteomics...

2023-06-13

[Animal modeling] - Application of ultrasound image in evaluating nodular Goitre in rats

To determine the thyroid localization of rats by using ultrasound technology, and analyze and evaluate the pathological changes and modeling degree of nodular Goitre model in rats, so as to provide technical methods for the diagnosis and evaluation o...

2023-06-13

[Animal modeling] - Taurine has no protective effect on corneal endothelial cells in rats injured by Benzalkonium chloride

To observe the protective effect of 2% taurine on endothelial cells of cornea injured by benzalkonium chloride in rats...

2023-06-13

【 Animal modeling 】 - The effect of aerobic exercise on the inhibitory synaptic transmission efficiency of dopamine neurons in VTA of nicotine withdrawal mice

To explore the effect of moderate intensity aerobic exercise on inhibitory Synaptic plasticity of VTA dopamine neurons in nicotine withdrawal mice, so as to provide some experimental evidence for reducing nicotine relapse by exercise...

2023-06-13

【 Traditional Chinese Medicine Model 】 - The Effect of Danggui Shengjiang Yangrou Tang on Traditional Chinese Medicine Syndrome of IBS-D Rats with Spleen and Kidney Yang Deficiency

To explore the traditional Chinese medicine syndrome manifestations of spleen and kidney yang deficiency model and observe the improvement effect of Danggui Shengjiang Yangrou Tang on traditional Chinese medicine syndrome in IBS-D female rats with sp...

2023-06-13