[Animal modeling] - Study on the safety and effectiveness of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice

To investigate the safety and efficacy of human umbilical cord mesenchymal stem cells (HUC-MSCs) in the treatment of lipopolysaccharide (LPS) - induced acute lung injury in mice...

2023-02-15

[Animal modeling] - Experimental study on the colonization of two strains of CRISPR engineered Escherichia coli in mice

To evaluate the colonization ability and efficiency of two Escherichia coli engineering strains, Nissle1917 and BW25113, in the intestinal tract by using mice, so as to screen out the strains with high colonization efficiency in the intestinal tract,...

2023-02-15

【Animal Modeling】-Effects of Noise Pollution on Blood Hormone and Hsp-70 Levels in Rats

To investigate the effects of noise pollution on blood hormone levels and expression of heat shock protein-70 (Hsp-70) in rats...

2023-02-14

【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

To analyze the modeling elements of asthma animal models, and to provide methodological reference for improving the success rate of modeling and evaluating the tested drugs effectively...

2023-02-14

【Animal modeling】-Study on the protective effect of Ginkgo biloba extract on MPTP-induced Parkinson\\

To observe the preventive effect of Ginkgo biloba extract on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson\\\'s mice of different ages...

2023-02-14

【Animal Modeling】-Effect of Bushen Yangxue Recipe on Anti-Müllerian Hormone in Rats with Premature Ovarian Failure

To establish a rat model of premature ovarian failure induced by Tripterygium wilfordii polyglycosides, and to study the effect of Bushen Yangxue Recipe on anti-mullerian in rats with premature ovarian failure...

2023-02-14

【Animal Modeling】-Screening reference genes with different expression abundances using expression profile chip data

Based on the detection results of expression profiling chip, multiple reference genes were screened for quantitative detection of genes with different expression abundances in the liver tissue of Mus musculus...

2023-02-13

【Animal modeling】-miR-144 negatively regulates the expression of TOLL-like receptor 2 in rat macrophages

To clarify the relationship between TOLL-like receptor 2 (TLR2) and the role of microRNA144 (miR-144)...

2023-02-13

[Animal modeling] - Study on the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury in rats

To investigate the effect of dexmedetomidine combined with sufentanil on pulmonary ischemia-reperfusion injury (LIRI) in rats...

2023-02-09

[Animal modeling] - Resveratrol passes through HIF-1 α/ BNIP3-mediated autophagy signal pathway promotes the repair of hypoxic brain injury in mice

To explore the effect of resveratrol through HIF-1 α/ The mechanism of BNIP3-mediated autophagy signal pathway promoting the repair of hypoxic brain injury in mice...

2023-02-09

[Animal modeling] - Study on the anti-colon cancer effect of five species of Ferula in Xinjiang based on cell and animal experiments

To study the effects of five kinds of ferula from Xinjiang and their different polar parts on the proliferation inhibition and apoptosis of human colon cancer HCT 116 cells in vitro, and to study the effects of five kinds of ferula from Xinjiang on c...

2023-02-09

[Animal modeling] - Cannabinol reduces the changes of monoamine neurotransmitter induced by methamphetamine in rats

To explore the effect of cannabinol on monoamine neurotransmitters in the central nervous system in methamphetamine dependent rats, explain the therapeutic mechanism of CBD on METH dependence, and provide reference for the development of drug depende...

2023-02-09

[Animal modeling] - Shenqi Pill reduces kidney damage in diabetes ZDF rats

To investigate the intervention effect of Shenqi Pill on renal injury in diabetes ZDF rats and whether its mechanism is to reduce ERS through PERK pathway...

2023-02-08

[Animal modeling] - Effect of matrine on endothelial injury and JAK2/STAT3/SOC1 signal pathway in pregnant hypertensive rats

To investigate the effect of matrine on endothelial injury and tyrosine protein kinase 2/signal transducer and activator of transcription 3/cytokine signal transcription inhibitor 1 (JAK2/STAT3/SOSC1) signal pathway in rats with pregnancy induced hyp...

2023-02-08

[Animal modeling] - Effect of skeletal muscle specific Chrono overexpression on exercise ability and glucose tolerance in mice

The level of skeletal muscle glucose metabolism is an important factor affecting aerobic exercise ability, and the level of skeletal muscle glucose metabolism is regulated by the biological clock...

2023-02-08

[Animal modeling] - Study on the detoxification and protection mechanism of grub peptide extract on lead induced nephrotoxicity in mice

To explore the mechanism of detoxification and protection of grub peptide extract on mice by establishing a lead acetate induced nephrotoxicity model in order to provide experimental basis for the prevention and treatment of lead induced nephrosis...

2023-02-08