【Animal Modeling】-Preliminary study on the structural and functional differences of reproductive system between fertile and infertile male naked mole rats

To observe and analyze the differences in reproductive system structure and function between fertile and infertile male naked mole-rats, and preliminarily explore the reasons why male infertile individuals cannot reproduce...

2022-11-14

【Animal modeling】-Combined with high-resolution MRI and micro-CT to evaluate the repairing effect of Taohong Siwu Decoction on femoral head necrosis in rabbits

To establish a rabbit model of steroid-induced necrosis of the femoral head (SIONFH), and to evaluate the repairing effect of Taohong Siwu Decoction (THSWD) on the damage of SIONFH microscopic bony structure combined with high-resolution MRI and micr...

2022-11-14

【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

To study the effects of camel milk (CM) on body weight, blood glucose, blood lipids, insulin, PPARγ and TNF-α gene expression in type 2 diabetic rats...

2022-11-14

【Animal modeling】-Safety evaluation of Japanese white rabbit skin irradiated by light-emitting diode light source

To irradiate the skin tissue of Japanese white rabbit with LED white light source, and to preliminarily evaluate the safety of LED light source irradiation...

2022-11-14

【Animal modeling】-The effect of 6-week free runner exercise on sex hormones and hypothalamic-pituitary-testis axis in high-fat-fed male rats

To observe the effect of high-fat diet on the structure of hypothalamus, pituitary, testis and sex hormone levels in adolescent male rats, and to explore the intervention effect of 6-week free wheel exercise...

2022-11-14

【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

To investigate the changes of hematological indexes in the long-term toxicity test of Niaotongkake Naiqi tablets in rats...

2022-11-11

【Animal modeling】-The improvement effect of Xueshuantong capsule on tight junction injury of HUVEC cells induced by oxygen-glucose deprivation/reoxygenation

To investigate the protective effects of Panax notoginseng saponins (PNS) and its monomers Rg1-Rb1 on the damage of vascular endothelial tight junctions induced by oxygen-glucose deprivation (OGD) in a model of HUVEC cells induced by oxygen-glucose d...

2022-11-11

【Animal modeling】-Changes and significance of protein expression of microRNA-97a and TGF-β1 in myocardial tissue of spontaneously hypertensive rats

To observe the expression changes and relationship between Micro RNA-97a and TGF-β1 protein in myocardial tissue of spontaneously hypertensive rats (SHR)...

2022-11-11

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleotide polymorphisms that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki rat, Brown-Norway (BN) rat, Sprague-Dawley (SD) rat] sex locus and verify its reliability...

2022-11-11

[Animal modeling] - Changes of monoamine neurotransmitter content and neurofactor expression in brain region of rats with anxiety and depression

To study the changes of monoamine neurotransmitters in hippocampus, amygdala and prefrontal cortex and the expression trend of neurotrophic factors in brain of anxiety depression model rats, and to explore its possible pathogenesis...

2022-11-11

【Animal Modeling】- Mouse spleen mesenchymal stem cells regulate the proliferation and activation of T lymphocytes

To study the regulatory effect of mouse spleen mesenchymal stem cells (Sp-MSCs) on the proliferation and activation of T lymphocytes...

2022-11-10

【Animal Modeling】-Buulfan on the Injury of Hematopoietic Stem Cell Function in Mice

To examine the effects of different administration methods on the function of hematopoietic stem cells in mice...

2022-11-10

【Animal Modeling】-Study on Intestinal Morphology and Energy Demand of Long-clawed Gerbils

To analyze the relationship between species differences and intestinal morphology and energy metabolism, and to clarify the energy requirements of gerbils...

2022-11-10

[Animal modeling] - Comparison of subcutaneous transplanted tumor models in different parts of Lewis lung cancer in mice

To explore the differences of subcutaneous transplantation of lung cancer in different parts of the body, and to provide a basis for lung cancer researchers...

2022-11-10

[Animal modeling] - Plasma metabonomics study on the model of type 2 diabetes rats with abnormal black gallbladder syndrome

To establish and analyze the characteristics of plasma metabonomics in type 2 diabetes (T2DM) rats with Uygur medicine abnormal black gallbladder syndrome...

2022-11-10

[Animal modeling] - Construction and preliminary application of xenotransplantation model of human liver cancer

To establish a xenotransplantation model of human hepatocellular carcinoma (HCC) and explore its role in precision medical treatment of HCC...

2022-11-10