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【Animal Modeling】-Establishment and preliminary analysis of the cynomolgus monkey model of hyperlipidemia

【Animal Modeling】-Establishment and preliminary analysis of the cynomolgus monkey model of hyperlipidemia

To establish a hyperlipidemia cynomolgus monkey model with similar characteristics of human diseases, and to provide an ideal animal model for the development of lipid-lowering drugs (especially biological lipid-lowering drugs)...

2022-08-29
【Animal Modeling】-Analysis of Mozart\'s K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

【Animal Modeling】-Analysis of Mozart\'s K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

To establish a depression model in C57BL/6 mice, and to preliminarily explore the effect of high-frequency sound waves in Mozart\'s K448 sonata on improving depressive symptoms in C57BL/6 mice...

2022-08-26
【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

To select a human hepatoma cell line that stably express a luciferase reporter gene, and to construct an in situ tumor-bearing nude mouse model of human hepatoma cell line...

2022-08-26
【Animal Modeling】-A study on the combination of disease and syndrome of atherosclerosis (Qi stagnation and blood stasis syndrome) in rats

【Animal Modeling】-A study on the combination of disease and syndrome of atherosclerosis (Qi stagnation and blood stasis syndrome) in rats

To construct a rat model of atherosclerosis (Qi stagnation and blood stasis syndrome) combined with disease and syndrome, and to provide an evaluation tool for the pharmacodynamics study of the corresponding traditional Chinese medicine...

2022-08-26
【Animal Modeling】-High-frequency right atrial pacing to establish a canine atrial fibrillation model and evaluation of implantable ECG monitors

【Animal Modeling】-High-frequency right atrial pacing to establish a canine atrial fibrillation model and evaluation of implantable ECG monitors

In the traditional conventional high-frequency atrial pacing modeling method, innovatively use fine electrode leads, advanced catheter control system and implantable ECG monitor to track the onset of atrial fibrillation, and observe the establishment...

2022-08-26
【Animal modeling】-Using CRISPR/Cas9 gene editing technology to establish a large FcγR gene knockout mouse model

【Animal modeling】-Using CRISPR/Cas9 gene editing technology to establish a large FcγR gene knockout mouse model

To use CRISPR/Cas9 gene editing technology to knock out the mouse FcγR2b, FcγR3, FcγR4 gene clusters with a length of about 90 kb, so as to lay the foundation for the construction of FcγR gene humanized mice...

2022-08-26
【Animal modeling】-Evaluation of motor perception behavior in non-human primate unilateral brain injury model

【Animal modeling】-Evaluation of motor perception behavior in non-human primate unilateral brain injury model

By evaluating the functional changes of brain regions related to brain perception and motor behavioral responses, it is an important strategy for clinical translational research on major brain diseases based on non-human primates in brain science res...

2022-08-26
【Animal modeling】-Establishment and optimization of mouse primary liver cancer model

【Animal modeling】-Establishment and optimization of mouse primary liver cancer model

To establish a mouse primary liver cancer model using three modeling methods, and to compare the advantages and disadvantages of each...

2022-08-26
【Animal Modeling】-Comparative study of three mouse models of early-onset ovarian insufficiency

【Animal Modeling】-Comparative study of three mouse models of early-onset ovarian insufficiency

To compare and analyze the differences of three commonly used modeling methods for early-onset ovarian insufficiency mouse models, and to explore the modeling methods that conform to the clinical characteristics of POI...

2022-08-26
【Animal Modeling】-Preliminary Study on Rhesus Monkey Model Infected by Human Coxsackie B2 Virus

【Animal Modeling】-Preliminary Study on Rhesus Monkey Model Infected by Human Coxsackie B2 Virus

To provide experimental methods and technical support for the establishment of human coxsackie B2 virus infection model in rhesus macaques by preliminarily analyzing the infection characteristics of human coxsackie B2 virus in rhesus monkeys through ...

2022-08-26
【Animal Modeling】-Establishment and evaluation of a mouse model of coronary heart disease-derived intestinal flora

【Animal Modeling】-Establishment and evaluation of a mouse model of coronary heart disease-derived intestinal flora

To establish a mouse model of coronary heart disease-derived intestinal flora by fecal bacteria transplantation and evaluate the model...

2022-08-26
【Animal modeling】-Protective effect of hemorrhoids magnetized ointment on mouse hemorrhoid model

【Animal modeling】-Protective effect of hemorrhoids magnetized ointment on mouse hemorrhoid model

To study the protective effect of hemorrhoid magnetization ointment on acetic acid-induced hemorrhoids in mice...

2022-08-26
【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

To comprehensively evaluate the improved method for establishing myocardial ischemia-reperfusion injury model in rats...

2022-08-26
【Animal modeling】-Establishment and evaluation of a rat model of chronic obstructive pulmonary disease

【Animal modeling】-Establishment and evaluation of a rat model of chronic obstructive pulmonary disease

To construct a rat model of chronic obstructive pulmonary disease by smoking method, protease instillation and a combination of the two methods...

2022-08-26
【Animal modeling】-Effect of platelet-rich plasma on the healing of rabbit Achilles tendon

【Animal modeling】-Effect of platelet-rich plasma on the healing of rabbit Achilles tendon

Surgical treatment of acute Achilles tendon rupture includes early accelerated rehabilitation which shortens the immobilization period, allowing early range of motion and muscle strengthening exercises...

2022-08-26
【Animal modeling】-Construction of myocardial iron overload rabbit model and study of iron deposition law

【Animal modeling】-Construction of myocardial iron overload rabbit model and study of iron deposition law

To investigate the method of making an animal model of myocardial iron deposition and the relationship between the iron deposition in the heart and liver...

2022-08-26