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【Animal Modeling】-Evaluation of the Validation Results for the Detection of Esterase-1 in the Serum of Experimental Mice

【Animal Modeling】-Evaluation of the Validation Results for the Detection of Esterase-1 in the Serum of Experimental Mice

Through the detection and comparison of esterase-1 in the serum of experimental mice, to promote the national laboratory animal quality testing laboratories to strengthen the quality control management and improve the detection ability...

2022-06-07
【Animal modeling】-Characterization of APP gene in tree shrew and identification of alternative spliceosomes

【Animal modeling】-Characterization of APP gene in tree shrew and identification of alternative spliceosomes

To distinguish and identify multiple alternative splices of APP gene mRNA in tree shrew, describe the characteristics of APP gene, and determine its expression distribution in various tissues...

2022-06-07
【Animal Modeling】-Tumorogenicity of High Five Insect Cell Line

【Animal Modeling】-Tumorogenicity of High Five Insect Cell Line

To test the tumorigenicity of High Five insect cell line to BALB/c nude mice, so as to ensure its safety as a vaccine production cell line...

2022-06-07
【Animal Modeling】- Improvement of the method for locating the supraoptic nucleus of the hypothalamus in rats

【Animal Modeling】- Improvement of the method for locating the supraoptic nucleus of the hypothalamus in rats

To improve the stereotaxic oblique puncture method in rats...

2022-06-07
【Animal modeling】-Dynamic histological observation of tooth germ development of mandibular first molars in ICR mice

【Animal modeling】-Dynamic histological observation of tooth germ development of mandibular first molars in ICR mice

To understand the developmental timing characteristics of the mandibular first molar tooth germ in ICR mice, and to provide an experimental basis for using mice to study the mechanism of tooth development and related influencing factors...

2022-06-07
【Animal Modeling】-Comparison of Organ Index and Hypoxia-Related Genes between Bama Pig and Bama Mini Pig

【Animal Modeling】-Comparison of Organ Index and Hypoxia-Related Genes between Bama Pig and Bama Mini Pig

To study the differences in organ index and expression of hypoxia-related genes between Bama pigs and Bama minipigs...

2022-06-07
【Animal Modeling】-Investigation of Natural Infection of Mouse Encephalomyelitis Virus and Experiment of Artificial Infection in Mice

【Animal Modeling】-Investigation of Natural Infection of Mouse Encephalomyelitis Virus and Experiment of Artificial Infection in Mice

To understand the natural infection of mouse encephalomyelitis virus (TMEV), and to explore the distribution of the virus in various organs and tissues and the changes of serum antibodies in mice artificially infected with TMEV...

2022-06-07
【Animal Modeling】-Preliminary study on knockout of MATP gene in mouse melanoma cell line using CRISPR-Cas9 system

【Animal Modeling】-Preliminary study on knockout of MATP gene in mouse melanoma cell line using CRISPR-Cas9 system

To use the CRISPR/Cas9 system to knock out the MATP gene in mouse melanoma cell lines, laying the foundation for the functional study of the MATP gene...

2022-06-07
【Animal Modeling】-Verification of the B2m gene silencing site in marmosets at the cellular level

【Animal Modeling】-Verification of the B2m gene silencing site in marmosets at the cellular level

To screen and verify the effective silencing target of marmoset B2m gene at the cellular level...

2022-06-07
【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

To study the depilation parameters of SD rat skin, and to provide basic experimental conditions for establishing skin photoaging animal model...

2022-06-06
【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

To compare the effects of two different samples of serum and plasma and different test methods on the measured values of blood biochemical indexes and blood glucose in rats...

2022-06-06
【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

To investigate the role and mechanism of miR-221 in hydrogen peroxide (H2O2)-induced rat cardiomyocyte (H9c2) injury...

2022-06-06
【Animal Modeling】-Fluorescence two-dimensional electrophoresis to detect the differences in liver tissue proteomics between male and female mice

【Animal Modeling】-Fluorescence two-dimensional electrophoresis to detect the differences in liver tissue proteomics between male and female mice

To detect the differences in the expression of proteomes in the liver tissue of male and female mice, and to explore the mechanism of gender differences in the occurrence of liver diseases...

2022-06-06
【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

To establish an in vitro model of intestinal epithelial cells—small intestinal organoid culture system, and to explore its related pathological detection techniques, so as to provide a convenient platform for the in vitro research of intestinal-relat...

2022-06-06
【Animal Modeling】-The mechanism of acute hyperglycemia affecting the first phase insulin secretion in mice

【Animal Modeling】-The mechanism of acute hyperglycemia affecting the first phase insulin secretion in mice

To observe the function and morphological changes of acute hyperglycemia affecting the first phase insulin secretion in mice...

2022-06-06
【Animal modeling】-pathological comparative analysis of BALB/c mice infected with herpes simplex virus type Ⅱ through different routes

【Animal modeling】-pathological comparative analysis of BALB/c mice infected with herpes simplex virus type Ⅱ through different routes

To compare the pathological changes of BALB/c mice infected with herpes simplex virus type Ⅱ (HSV-2) by different routes...

2022-06-06