【Animal Modeling】-Comparison of the genetic structure of two experimental mouse populations using microsatellite technology

To compare the genetic structure of two experimental mouse populations using microsatellite markers...

2022-05-07

【Animal modeling】- Breeding and genotype identification of Bmal1 clock gene knockout mice

To breed and identify the genotype of Bmal1 knockout mice to provide an ideal animal model for biological rhythm research...

2022-05-07

【Animal modeling】-Effect of p53 knockout on neurobehavior and the number of neurons in barrel cortex in mice

To explore the role of p53 gene in neurobehavioral activity in mice and its effect on the number of neurons in barrel cortex...

2022-05-07

【Animal modeling】-Establishment and preliminary application of FO-PCR detection method for mouse pox virus

To establish a TaqMan probe-based fluorescent quantitative PCR detection method for mouse pox virus (ECTV), and to detect the nude mole rat tissue samples, mouse tissue samples and chinchilla tissue samples preserved in the laboratory...

2022-05-07

【Animal Modeling】-Relationship between vascular calcification and bone metabolism markers in rats with chronic kidney disease

To study the correlation between vascular calcification and serum bone metabolism markers in chronic kidney disease (CKD) rats...

2022-05-07

【Animal Modeling】Effect of -60Coγ-ray radiation on the spleen of naked mole rats

To observe the changes of spleen immune system and tissue biochemical indexes in naked mole-rats after 60Co γ-ray irradiation, and to preliminarily understand the radiation tolerance characteristics of naked mole-rats spleen...

2022-05-07

【Animal modeling】-Prnp-SNCA-A53T Parkinson\'s disease transgenic mice with different intestinal flora

A number of evidences indicate that the intestinal flora of Parkinson\'s disease patients is abnormal, and whether Prnp-SNCA-A53T Parkinson\'s disease transgenic mice also have intestinal flora dysbiosis has not been reported. Microbial ecological ch...

2022-05-07

【Animal Modeling】-Expression and distribution of protein degradation pathway regulatory molecules in mouse nervous system

To investigate the expression and distribution of regulatory molecules of cellular protein degradation pathway in mouse nervous system...

2022-05-06

【Animal modeling】-Isolation and identification of exosomes from skin fibroblasts of naked mole rats

To isolate and culture naked mole rat skin fibroblasts, identify them, and explore whether naked mole rat skin fibroblasts have the ability to secrete exosomes...

2022-05-06

【Animal Modeling】-miR-122 Expression Changes and Action Mechanisms in Kidney Tissues of Mice with Diabetic Nephropathy

To investigate the expression changes of miR-122 in the kidney tissue of diabetic nephropathy mice and the effect and possible mechanism of silencing miR-122 on the kidney tissue of DN mice...

2022-05-06

【Animal Modeling】-Changes in the structure and function of the immune system of SD rats during natural aging

To observe the changes in the structure and function of the immune system in naturally aged SD rats, and to explore the possible mechanisms?...

2022-05-06

【Animal Modeling】-Optimization of PCR detection method for Pasteurella pneumophila in mice and its preliminary application in different sample processing

To establish a real-time, rapid, sensitive and simple PCR method for the detection of Pasteurella pneumophila in living experimental animals...

2022-05-06

【Animal Modeling】-Small ubiquitin-like modifier protease 3 regulates autophagy in mouse alveolar type II epithelial cells

To investigate the regulatory effect and molecular mechanism of small ubiquitin-like modifier-specific protease 3 on autophagy in mouse lung tissue...

2022-05-06

【Animal modeling】-Validation of the effect of SPF golden hamster cage and drinking water pulsed vacuum sterilization

To confirm the performance of the pulse vacuum sterilizer, and to verify the effect of pulse vacuum sterilization on the SPF golden hamster cage and drinking water under the specified loading method and sterilization conditions...

2022-05-06

【Animal modeling】-Comparative analysis of single nucleotide polymorphisms and alternative splicing before and after vitrification of bovine blastocysts

【Animal Modeling】-Comparative Study on Fine Behavior of Mouse Spinal Cord Injury Strike Model...

2022-05-05

【Animal Modeling】-Comparative Study on Fine Behavior of Mouse Spinal Cord Injury Strike Model

To investigate the abnormal performance of fine behaviors in home cages, such as voluntary movement, exploratory behavior and self-care behavior, in addition to motor dysfunction in mice with spinal cord injury...

2022-05-05