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【Animal modeling】-bcl-2 gene-modified neural stem cell transplantation to repair spinal cord injury in rats

【Animal modeling】-bcl-2 gene-modified neural stem cell transplantation to repair spinal cord injury in rats

To investigate the effect of bcl-2 gene-modified neural stem cell transplantation on the recovery of injured nerve function in rats with spinal cord injury...

2022-04-26
【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

To compare the ulcer wound healing characteristics of C57BL/6J-db/db and STZ-induced C57BL/6J mice with type 2 diabetes mellitus commonly used at present, and to conduct relevant animal experiments for the application of a stable diabetic mouse ulcer...

2022-04-26
【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

To investigate whether VEGF-A inhibitor sFLT-1 can reverse the renal damage in type 1 diabetic mice by inhibiting the activation and inflammatory response of vascular endothelial cells...

2022-04-26
【Animal modeling】-The expression and ultrastructural observation of kidney-yang deficiency-related mRNA in the hypothalamus of Lewis rats

【Animal modeling】-The expression and ultrastructural observation of kidney-yang deficiency-related mRNA in the hypothalamus of Lewis rats

To further study the kidney-yang deficiency constitution of Lewis rats by observing the gene expression and ultrastructure related to kidney-yang deficiency in the hypothalamus of Lewis rats...

2022-04-26
【Animal modeling】-Effect of Naoshuantong capsule on the expression of inflammatory factors in aorta of ApoE-/- mice

【Animal modeling】-Effect of Naoshuantong capsule on the expression of inflammatory factors in aorta of ApoE-/- mice

To observe the effect of Naoshuantong capsule on the expression of inflammatory related factors interleukin-1β, interleukin-6, tumor necrosis factor, intercellular adhesion molecule-1 and metalloproteinase-9 in ApoE-/- atherosclerosis mouse model. Th...

2022-04-26
【Animal modeling】-The role of KA1 subreceptors in the death of hippocampal neurons induced by endoplasmic reticulum stress

【Animal modeling】-The role of KA1 subreceptors in the death of hippocampal neurons induced by endoplasmic reticulum stress

To explore the role of up-regulated expression of KA1 sub-receptors in the death of hippocampal neurons induced by endoplasmic reticulum stress...

2022-04-26
【Animal Modeling】-Improved method to explore and extract rat dorsal root ganglia against the direction of nerve walking

【Animal Modeling】-Improved method to explore and extract rat dorsal root ganglia against the direction of nerve walking

Explore a new method of fast, convenient and efficient extraction of rat dorsal root ganglia (dorsal root ganglion, DRG)-exploring and extracting DRG against the direction of nerve walking...

2022-04-26
【Animal Modeling】-Observation of neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms

【Animal Modeling】-Observation of neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms

To investigate the neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms...

2022-04-26
【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

To explore the effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats...

2022-04-26
【Animal modeling】-Effect of angiotensin (1-7) on the expression of GFAP, GDNF and cognitive function in the hippocampus of diabetic rats

【Animal modeling】-Effect of angiotensin (1-7) on the expression of GFAP, GDNF and cognitive function in the hippocampus of diabetic rats

To observe the effect of angiotensin (1-7) [Ang (1-7)] on the expression of glial fibrillary acidic protein (GFAP), glial cell-derived neurotrophic factor (GDNF) and cognitive function in the hippocampus of diabetic rats. influence...

2022-04-26
【Animal modeling】-Effect of Naoshuantong capsule on the expression of inflammatory factors in aorta of ApoE-/- mice

【Animal modeling】-Effect of Naoshuantong capsule on the expression of inflammatory factors in aorta of ApoE-/- mice

To observe the effect of Naoshuantong capsule on the expression of inflammatory related factors interleukin-1β, interleukin-6, tumor necrosis factor, intercellular adhesion molecule-1 and metalloproteinase-9 in ApoE-/- atherosclerosis mouse model...

2022-04-26
【Animal modeling】-Combined with high-resolution MRI and micro-CT to evaluate the repairing effect of Taohong Siwu Decoction on femoral head necrosis in rabbits

【Animal modeling】-Combined with high-resolution MRI and micro-CT to evaluate the repairing effect of Taohong Siwu Decoction on femoral head necrosis in rabbits

To establish a rabbit model of steroid-induced necrosis of the femoral head, and to evaluate the repairing effect of Taohong Siwu Decoction (THSWD) on the microscopic bone structure damage of SIONFH combined with high-resolution MRI and micro-CT...

2022-04-26
【Animal Modeling】-Comparison of the biological characteristics of the eyeball of two guinea pig strains and research on the mechanism of retinal myopia

【Animal Modeling】-Comparison of the biological characteristics of the eyeball of two guinea pig strains and research on the mechanism of retinal myopia

To compare the biological characteristics of the eyeballs of Zmu-1:DHP and DHP guinea pigs, and to preliminarily explore the retina-related mechanism of spontaneous myopia in Zmu-1:DHP guinea pigs...

2022-04-25
[Animal modeling]-Diphtheria toxin-induced myocarditis in mice

[Animal modeling]-Diphtheria toxin-induced myocarditis in mice

Reproduction method For experimental mice weighing 25 to 30 g, first observe the experimental animals for 3 days, select healthy animals as models, and then pass the diphtheria toxin stock solution of 7.30 μg/g body weight through the tail of the mou...

2022-04-25
【Animal Modeling】-Guinea Pig Pulmonary Tuberculosis Model

【Animal Modeling】-Guinea Pig Pulmonary Tuberculosis Model

The reproduction method uses female Hartley guinea pigs. In the middle of the logarithmic growth phase, dilute Mycobacterium tuberculosis with sterile redistilled water to the required inoculation concentration, and add 5 ml of distilled water contai...

2022-04-25
【Animal Modeling】-A Modified Rat Jugular Vein Intubation for Autonomous Drug Administration and Its Application

【Animal Modeling】-A Modified Rat Jugular Vein Intubation for Autonomous Drug Administration and Its Application

To introduce an improved rat jugular vein cannula fabrication method and jugular vein cannulation operation method, and apply it to an experimental study of autonomous drug administration in rats to evaluate the service life and application effect of...

2022-04-25