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【Animal modeling】-Effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

【Animal modeling】-Effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

To investigate the effect of artificial recombinant botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rats with spinal cord injury in vivo, and to provide a basis for elucidating the mechani...

2022-03-29
【Animal modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

【Animal modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

To construct the eukaryotic expression vector pEGFP N1/IL-37b of full-length and mature IL-37b, and to detect the expression of both in RAW 264.7 cells...

2022-03-29
【Animal Modeling】-Injury effect of high-frequency electromagnetic radiation on emotion-cognitive behavior in mice

【Animal Modeling】-Injury effect of high-frequency electromagnetic radiation on emotion-cognitive behavior in mice

To explore the establishment of a model of mouse emotional-cognitive behavioral damage caused by high-frequency electromagnetic radiation, and to provide an experimental basis for the study of radiation damage mechanism and protection...

2022-03-29
【Animal Modeling】-Using TaqMan probe fluorescence quantitative PCR technology to identify the genotype of Leprdb/+ mice offspring

【Animal Modeling】-Using TaqMan probe fluorescence quantitative PCR technology to identify the genotype of Leprdb/+ mice offspring

To establish an efficient method for genotyping the offspring of Leprdb/ + mice using TaqMan probe fluorescence quantitative PCR technology...

2022-03-29
【Animal modeling】-Blocking macrophage-mediated PD1/PD-L1 pathway inhibits tuberculosis recurrence in mice

【Animal modeling】-Blocking macrophage-mediated PD1/PD-L1 pathway inhibits tuberculosis recurrence in mice

To block the macrophage-mediated PD1/PD-L1 pathway with functional PD-L1 monoclonal antibody, and to study its immune intervention effect and mechanism on the relapse of tuberculosis in mice after treatment...

2022-03-29
【Animal Modeling】-Effect of 4-week ladder-climbing resistance training on hypoxia-induced skeletal muscle atrophy in rats

【Animal Modeling】-Effect of 4-week ladder-climbing resistance training on hypoxia-induced skeletal muscle atrophy in rats

To explore the effect of resistance training against hypoxia-induced skeletal muscle atrophy, and to provide a theoretical basis for solving the problem of skeletal muscle loss in athletes during altitude training...

2022-03-28
【Animal modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

【Animal modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

To investigate the protective effect of mild hypothermia on radiation-induced lung injury, and to compare the protective effect with amifostine, a commonly used clinical anti-radiation drug...

2022-03-28
【Animal modeling】-The effect of Dendrobium officinale polysaccharide on chronic atrophic gastritis in rats and its molecular mechanism

【Animal modeling】-The effect of Dendrobium officinale polysaccharide on chronic atrophic gastritis in rats and its molecular mechanism

To investigate the effect and molecular mechanism of Dendrobium officinale polysaccharide on nitrosoguanidine-induced chronic atrophic gastritis in rats...

2022-03-28
【Animal modeling】-Effect of emodin on fat browning in ApoE knockout mice

【Animal modeling】-Effect of emodin on fat browning in ApoE knockout mice

To observe the effect of emodin on fat browning in apolipoprotein E knockout mice, so as to explore its mechanism of improving blood stasis states such as hyperlipidemia...

2022-03-28
【Animal Modeling】-Effect of Xingnao Zaizao Capsule on memory impairment induced by formaldehyde in mice

【Animal Modeling】-Effect of Xingnao Zaizao Capsule on memory impairment induced by formaldehyde in mice

To investigate the effect of Xingnao Zaizao capsule on the memory impairment induced by formaldehyde in mice and its mechanism...

2022-03-28
【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

To explore the effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats...

2022-03-28
【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

To explore the therapeutic effect of anti-complement 5a receptor (C5aR) antibody combined with allicin on inflammatory bowel disease (IBD) in rats...

2022-03-25
【Animal Modeling】-Construction of Raf-1 Gene Recombinant Adenovirus siRNA Vector and Its Effect on Rat Cardiomyocyte Hypertrophy

【Animal Modeling】-Construction of Raf-1 Gene Recombinant Adenovirus siRNA Vector and Its Effect on Rat Cardiomyocyte Hypertrophy

To construct a recombinant adenovirus vector that specifically inhibits the Raf-1 gene in rats, and transduce it into rat cardiomyocytes in vitro for functional validation...

2022-03-25
How to prepare a rat model of Parkinson\\\\

How to prepare a rat model of Parkinson\\\\

Modeling materials Animal: SD rat, male, body weight (200±10) g; drug: manganese chloride reagent...

2022-03-25
【Animal modeling】-Protective effect of Apelin-13 on focal cerebral ischemia-reperfusion injury in rats

【Animal modeling】-Protective effect of Apelin-13 on focal cerebral ischemia-reperfusion injury in rats

To discuss the maintenance effect of Apelin-13 on focal cerebral ischemia-reperfusion injury (CIRI) in rats and its possible mechanism...

2022-03-25
【Animal modeling】-Effect of maca combined with exercise therapy on renal mitochondrial respiratory chain enzyme activity and renal function in diabetic rats

【Animal modeling】-Effect of maca combined with exercise therapy on renal mitochondrial respiratory chain enzyme activity and renal function in diabetic rats

To observe the effect of maca combined with exercise therapy on renal mitochondrial respiratory enzyme activity and renal function in diabetic rats...

2022-03-25