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To construct a taurine transporter knockout rat by CRISPR/Cas9 technology, breed and identify it, and provide a stable rat model for studying the effect of taurine deficiency on nervous system diseases...
2022-03-09To investigate the regulatory effects of nuclear transcription factors TRB, RXR and agonist T4 on Cip4 gene expression in gerbils...
2022-03-09To use the heat pipe air heat exchanger to exchange heat with the gas discharged from the laboratory animal facility, recover the temperature energy in the exhaust gas, and use the recovered energy in the fresh air to reduce the energy consumption of...
2022-03-08To analyze the expression of IL-18 in the intestinal tissue of tree shrew and the changes of intestinal flora under the action of D-galactose...
2022-03-08To compare the differences of peripheral blood and immune cell typing indexes between aged SD rats and young SD rats...
2022-03-08To investigate the genetic and immunological mechanisms of guinea pigs resistance to foot-and-mouth disease virus (FMDV). To elucidate the feasibility of FMDV pseudovirus-infected cells for studying FMDV pathogenesis...
2022-03-08Coxsackievirus A16 is one of the main pathogenic pathogens of hand, foot and mouth disease, and its pathogenic mechanism is not yet clear....
2022-03-08To screen and verify the conditions of electroporation for transfection of TRIB3 overexpression plasmid and TRIB3 siRNA in RAW264.7 cells, and to establish the optimal electroporation transfection scheme for RAW264.7 cells...
2022-03-08To explore the changes of cognitive function, motor function, anxiety-like behavior and pathological changes in α-synuclein A53T transgenic mice...
2022-03-08To study the inclusion of SMN2 exon 7 in different tissues of SMA mice, and to screen the related splicing factors...
2022-03-08To provide theoretical and technical support for microbial detection of imported experimental monkeys and how to carry out feeding management and disease prevention and control by identifying and drug susceptibility testing of Proteus mirabilis isola...
2022-03-08To establish a pig model of deep second-degree scald, and to observe the histopathological changes of skin repaired at different time points...
2022-03-08Whether circovirus 2 can infect human cells has been a topic of debate...
2022-03-08To establish a purification method for cytomegalovirus in mice to obtain mice without MCMV infection...
2022-03-07To clarify the expression location and level of TRIM26 in different tissues and organs of human and mouse...
2022-03-07To obtain the full-length coding sequence of junctional adhesion molecule A in tree ferrets and analyze its molecular characteristics, and to explore the mechanism of JAM-A as a receptor for reovirus invading primary lung cells of tree ferrets...
2022-03-07