【Animal modeling】-The treatment and mechanism of hemin on gestational hypertensive rats

To preliminarily explore the therapeutic effect and possible regulatory mechanism of heme oxygenase inducer hemin (Hemin) in rats with pregnancy-induced hypertension (HDCP)...

2022-02-09

【Animal modeling】- Oral human alpha interferon transforms Bifidobacterium to promote the proliferation and maturation of mouse lymphocytes

To investigate the regulatory effect of human alpha interferon (IFN-α) gene on the immune function of mice after oral administration of Bifidobacterium transformed...

2022-02-09

【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

To investigate the effect and mechanism of LXRα RNA interference (RNAi) in improving liver function in rats with fatty liver after liver transplantation...

2022-02-09

【Animal modeling】-Effect of acute incision pain on the expression of connexin Cx43 in the dorsal horn of spinal cord in rats

To observe the effect of acute incision pain on the expression of connexin43 (Cx43) in the dorsal horn of rat spinal cord...

2022-02-09

【Animal Modeling】-Effects of propofol on tumor lung metastasis and the expression of MTA1 and Wnt1 in tumor-bearing rats

To discuss the effect of different doses of propofol on the expression of MTA1 and Wnt1 in rat MADB106 cells lung metastasis and tumor tissue...

2022-02-09

【Animal modeling】-Subacute inhalation toxicity study of ivermectin original drug in rats

To study the subacute inhalation toxicity of ivermectin original drug to rats and find out the maximum ineffective dose...

2022-02-09

【Animal modeling】-Effect of rapamycin on proliferation of rat aortic valve interstitial cells

To apply rapamycin to target mTOR and discuss its effect on the proliferation of rat heart valve interstitial cells...

2022-02-09

【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

To observe the expression changes of Ghrelin on DKK-1 and WNT signaling pathways in diabetic rats, and to explore the mechanism involved in learning and memory function...

2022-02-09

【Animal modeling】-Protective effect of piperphentonamine hydrochloride on gentamicin-induced hearing loss in guinea pigs

To investigate the relationship between the expression of autophagy-related proteins beclin1 and LC3, Na+-K+-2Cl-binding transporter (NKCC1) mRNA, endothelin (ET) and cochlear gentamicin (GM) injury in guinea pig cochlea and piperphentonamine hydroch...

2022-02-09

【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

To study the genotoxicity of aniline and its repair kinetics...

2022-02-09

【Animal modeling】-Effect of octachlorodibenzodioxin on gene expression profile of mouse testis tissue

To discuss the effect of octachlorodibenzodioxins on the alteration of gene expression profiles in the testis of male mice...

2022-02-09

【Animal modeling】-Protective effect of acupuncture combined with Danhong injection on cerebral ischemia-reperfusion injury in rats

To study whether acupuncture for separation of Danhong injection has protective effect on cerebral ischemia-reperfusion injury in rats...

2022-02-09

【Animal modeling】-Repair effect of embryonic stem cells on ischemia-damaged myocardium in pregnant mice

Discuss whether fetal mouse embryonic stem cells can enter the pregnant mother through the blood circulatory system and stop the repair of ischemic myocardial tissue in pregnant mice...

2022-02-09

【Animal Experiments】-Effects of Four Commonly Used Experimental Anesthetics on Cardiovascular System of Rats

To discuss the effects of different animal experimental anesthetics on the cardiovascular system of rats...

2022-02-09

【Animal modeling】-Effect of miR-126 on myocardial cell apoptosis in rats with acute myocardial infarction

To investigate the effect of miR-126 on myocardial cell apoptosis in acute myocardial infarction (AMI) rats...

2022-02-08

【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

To use 16S rRNA high-throughput sequencing method to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and to compare and analyze the oral flora o...

2022-02-08