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【Animal Modeling】-High-fat feeding combined with common carotid artery balloon injury to make insulin resistant rabbit atherosclerosis model

【Animal Modeling】-High-fat feeding combined with common carotid artery balloon injury to make insulin resistant rabbit atherosclerosis model

Explore the method of establishing a fast, stable and reliable rabbit atherosclerosis (AS) model...

2022-01-13
【Animal Modeling】-What is the growth hormone receptor gene knockout mouse model?

【Animal Modeling】-What is the growth hormone receptor gene knockout mouse model?

Growth hormone (GH) synthesized and secreted by the pituitary gland not only regulates the growth and development of the body, but also plays an important regulatory role in many metabolic disorders. The biological function of GH is that it is activa...

2022-01-13
【Animal Modeling】-Miniature pig gastric ulcer model

【Animal Modeling】-Miniature pig gastric ulcer model

Peptic ulcer refers to the damage to the gastrointestinal mucosa caused by the digestion of gastric digestive juice itself....

2022-01-13
【Animal Modeling】-Mice Sepsis Model

【Animal Modeling】-Mice Sepsis Model

Establish and evaluate a mouse sepsis model, study the pathogenic mechanism of sepsis, and provide model animals for the development of anti-inflammatory drugs...

2022-01-13
【Disease animal model】-small pig acute liver failure model

【Disease animal model】-small pig acute liver failure model

Acute liver failure (ALF) is a clinical syndrome caused by large-scale hepatocyte necrosis in a short period of time. It is usually characterized by coagulopathy, extensive and extensive hepatocyte necrosis, hepatic encephalopathy and multiple organ...

2022-01-13
Comparative study of spontaneous and induced type 2 diabetes in mice

Comparative study of spontaneous and induced type 2 diabetes in mice

To compare the differences between spontaneous and induced type 2 diabetes mouse models in terms of glucose metabolism, insulin resistance and inflammation...

2022-01-13
【Animal Modeling】-Mice Acute Myocardial Infarction Model

【Animal Modeling】-Mice Acute Myocardial Infarction Model

...

2022-01-13
【Animal model】-Rotenone-induced Parkinson\\

【Animal model】-Rotenone-induced Parkinson\\

Modeling material animal: Lewis rat, male, weighing 260-280g; drug: rotenone. 2. Modeling method Rotenone (1.0 g/L) was dissolved in a mixed solvent of dimethyl sulfoxide: normal saline (2:1), the normal control group was injected subcutaneously with...

2022-01-13
What is a lipid-lowering model? -【Animal Modeling】

What is a lipid-lowering model? -【Animal Modeling】

Hyperlipidemia is a disease of lipid metabolism disorder. It is the main cause of cardiovascular and cerebrovascular diseases (such as coronary heart disease, stroke and atherosclerosis). It endangers the health of all people and has become exposed t...

2022-01-13
【Animal Modeling】-TAK1 inhibitor affects MAPK and NF-κB signaling pathways in diabetic rats and its renal protection mechanism

【Animal Modeling】-TAK1 inhibitor affects MAPK and NF-κB signaling pathways in diabetic rats and its renal protection mechanism

Discuss the effect of TAK1 inhibitor on MAPK and NF-κB signaling pathways in diabetic rats and its mechanism of kidney maintenance...

2022-01-13
【Animal Modeling】-Experimental study on establishing rat obesity model with high-calorie feed

【Animal Modeling】-Experimental study on establishing rat obesity model with high-calorie feed

Observe the effect of using high-calorie feed to establish a rat obesity model, as well as the differences in modeling between the two species of rats, and compare different obesity evaluation methods and obesity-sensitive animal screening methods, a...

2022-01-12
[Animal Modeling]-Mutations in the mother’s mitochondrial DNA will reduce the lifespan of the child

[Animal Modeling]-Mutations in the mother’s mitochondrial DNA will reduce the lifespan of the child

A study published in \\\\\\\"Science Reports\\\\\\\" turned mice into humans, so the life span of humans may be determined to a certain extent before birth...

2022-01-12
[Animal modeling] The effect and mechanism of 2,3-butanedione monooxime in improving calcium abnormalities in isolated rat hearts

[Animal modeling] The effect and mechanism of 2,3-butanedione monooxime in improving calcium abnormalities in isolated rat hearts

To explore the effect and mechanism of contracture inhibitor 2, 3-butane monooctane (BDM) in improving calcium abnormalities in isolated rat hearts...

2022-01-12
【Disease Animal Model】-Genetically Modified Basal Cell Carcinoma Model

【Disease Animal Model】-Genetically Modified Basal Cell Carcinoma Model

It is currently believed that the cause of BCC is mainly related to the abnormal activation of Shh signaling pathway (Sonic hedgehog signaling pathway, Shh)...

2022-01-12
【Animal Modeling】-Blunted cataract model

【Animal Modeling】-Blunted cataract model

Copy method After mydriasis, examine four-week-old female rats with a slit lamp to rule out corneal diseases, uveal diseases, lens and vitreous diseases...

2022-01-12
How to establish a rabbit sinus node injury model caused by formaldehyde? -【Animal Modeling】

How to establish a rabbit sinus node injury model caused by formaldehyde? -【Animal Modeling】

Establishment of a rabbit sinus node injury model induced by formaldehyde...

2022-01-12