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[Animal Modeling]-Effect of Naoshuantong Capsules on the Expression of Inflammatory Factors in ApoE-/- Mice

[Animal Modeling]-Effect of Naoshuantong Capsules on the Expression of Inflammatory Factors in ApoE-/- Mice

To observe the effects of Naoshuantong Capsules on the inflammation-related factors interleukin-1β (interleukin-1 beta, IL-1β), interleukin-6 (interleukin-6, IL-6) and tumors in ApoE-/- atherosclerosis mouse model. Necrosis factor (tumor necrosis fac...

2021-12-31
【Animal Modeling】-Hydrogen peroxide induces related changes in rat uterine ligament fibroblasts in vitro

【Animal Modeling】-Hydrogen peroxide induces related changes in rat uterine ligament fibroblasts in vitro

To explore the effects of oxidative stress on the proliferation, apoptosis, collagen synthesis and expression of inflammatory factors in uterine ligament fibroblasts and possible mechanisms...

2021-12-31
[Animal Modeling]-Changes and Significance of Arterial Blood Gas Analysis Indexes in Rats with Chronic Hypoxic Pulmonary Hypertension

[Animal Modeling]-Changes and Significance of Arterial Blood Gas Analysis Indexes in Rats with Chronic Hypoxic Pulmonary Hypertension

To investigate the changes and significance of arterial blood gas analysis indexes in a rat model of hypoxic pulmonary hypertension induced by chronic hypoxia...

2021-12-31
【Animal Modeling】-Protective effect of estrogen on oxidative stress damage of mouse osteoblast MC3T3-E1 and its mechanism

【Animal Modeling】-Protective effect of estrogen on oxidative stress damage of mouse osteoblast MC3T3-E1 and its mechanism

To explore the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1...

2021-12-31
[Animal modeling]-Increased serotonin can prevent mice from becoming addicted to cocaine

[Animal modeling]-Increased serotonin can prevent mice from becoming addicted to cocaine

Researchers report that elevated serotonin levels can prevent mice from compulsive seeking and addiction to cocaine...

2021-12-31
[Animal Modeling]-Emphysema animal model

[Animal Modeling]-Emphysema animal model

The solution is placed in a sealed reproductive method test guinea pig (male or female) ventilated isolation bag, then exposed to tobacco smoke, daily (10 rows/time, once/day, 5D)/1 week, 1, 3, 6, and 12 Month, lung histopathology and lung function t...

2021-12-31
【Animal Modeling】-Effects of Oct4 and Cdx2 on the differentiation of inner cell mass and trophectoderm of bovine embryo

【Animal Modeling】-Effects of Oct4 and Cdx2 on the differentiation of inner cell mass and trophectoderm of bovine embryo

Objective To study the effects of Oct4 and Cdx2 knockdown on the expression of genes related to the differentiation of bovine ICM and TE, and to explain the role of Oct4 and Cdx2 in the early development of bovine embryos...

2021-12-31
【Animal Modeling】-The effect of alprostadil on eIF2α/ATF4/CHOP pathway and liver function in rats with fulminant liver failure

【Animal Modeling】-The effect of alprostadil on eIF2α/ATF4/CHOP pathway and liver function in rats with fulminant liver failure

 Objective To explore the effect of alprostadil (PGE1) on liver function in rats with fulminant hepatic failure (FHF), and to explore its effect on eukaryotic translation initiation factor 2α (eIF2α) / activating transcription factor 4 (ATF4) / C/ EB...

2021-12-31
[Animal Modeling]-Ke Shan Ting regulates skin inflammation and autophagy in mice with psoriasis by inhibiting C5a/C5aR1 pathway

[Animal Modeling]-Ke Shan Ting regulates skin inflammation and autophagy in mice with psoriasis by inhibiting C5a/C5aR1 pathway

This study intends to use imiquimod (IMQ) mouse psoriasis model to explore the regulation effect of Cosentyx on skin inflammation and autophagy in psoriasis mice through the C5a / C5aR1 pathway...

2021-12-31
【Animal Modeling】-The effect of salidroside on Nrf2/Keap1 signaling pathway and wound healing in rats with diabetic foot ulcer

【Animal Modeling】-The effect of salidroside on Nrf2/Keap1 signaling pathway and wound healing in rats with diabetic foot ulcer

Objective To explore the effects of salidroside (Sal) on the nuclear transcription factor E2 related factor 2 / Kelch-like epichlorohydrin related protein 1 (Nrf2 / Keap1) signaling pathway and wound healing in rats with diabetic foot ulcer (DFU)...

2021-12-31
【Animal Modeling】-Cyno-eating monkey muscle atrophy model

【Animal Modeling】-Cyno-eating monkey muscle atrophy model

Establish an animal model of cynomolgus muscle atrophy, and use the method of restricting the movement of the lower limbs to establish a model evaluation method?...

2021-12-30
[Animal Modeling]-Chronic Renal Insufficiency Model

[Animal Modeling]-Chronic Renal Insufficiency Model

Establish a C57BL/6 mouse model of chronic kidney disease, explore the changes in tubule damage indexes and interstitial fibrosis with the dose of cisplatin, and provide animal experimental evidence for the study of the progression from AKI to CKD...

2021-12-30
【Animal modeling】-BALB/c mouse model of total hysterectomy

【Animal modeling】-BALB/c mouse model of total hysterectomy

How to establish a BALB/c mouse total hysterectomy experimental animal model, and investigate and analyze the characteristics and formation mechanism of the model...

2021-12-30
【Animal Modeling】-Animal Model of Depression

【Animal Modeling】-Animal Model of Depression

Neurobiochemical function change model...

2021-12-30
【Animal Modeling】-6-Hydroxydopamine-induced Parkinson\\

【Animal Modeling】-6-Hydroxydopamine-induced Parkinson\\

Animal: SD rat, female, 2 to 3 months old, weighing 180 to 220 g; drug: 6-hydroxydopamine (6-OHDA), apomorphine, rabbit anti-tyrosine hydroxylase serum, parent Avidin-biotin-peroxidase complex (ABC) kit; equipment: rat brain stereotaxic instrument, 3...

2021-12-30
【Animal Modeling】-Foam Cell Model

【Animal Modeling】-Foam Cell Model

The pathological changes of atherosclerosis include lipid streaks, fibrous plaques, atherosclerotic plaques, compound lesions, etc., while foam cells are the early cytological features of As lesions...

2021-12-30