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【Animal Modeling】-How to use targeted near-infrared fluorescent dyes in liver cancer models?

【Animal Modeling】-How to use targeted near-infrared fluorescent dyes in liver cancer models?

Explore the application of near-infrared fluorescence (IRRF) dye IR-783 in liver cancer model imaging research, and analyze the molecular mechanism of the dye targeting tumor cells...

2021-05-26
【Animal Modeling】-How to establish a rat model of diarrhea-type irritable bowel syndrome?

【Animal Modeling】-How to establish a rat model of diarrhea-type irritable bowel syndrome?

By observing the changes in rat symptoms, histopathology, visceral hypersensitivity, mast cell activation, autophagy, beclin-1 and claudin-2 and other related indicators, capsaicin gavage was performed. Symptoms of diarrheal irritable bowel syndrome ...

2021-05-26
【Animal Modeling】-Why use optogenetic technology to prepare animal models of nervous system diseases?

【Animal Modeling】-Why use optogenetic technology to prepare animal models of nervous system diseases?

Parkinson\\\'s disease, depression, anxiety, Alzheimer\\\'s disease and other neuropsychiatric diseases seriously endanger human health and cause a heavy burden on medical care...

2021-05-26
【Animal Modeling】-How to build a porcine myocardial infarction model of Potentilla hemp?

【Animal Modeling】-How to build a porcine myocardial infarction model of Potentilla hemp?

Establish the myocardial infarction model and clinically important model indicators in goose Potentilla piglets, and explore the correlation between the gene expression of myocardial infarction marginal zone and metabolic compensation...

2021-05-25
【Animal Modeling】-What are the pathological mechanisms of the asthma mouse model under the action of paeoniflorin?

【Animal Modeling】-What are the pathological mechanisms of the asthma mouse model under the action of paeoniflorin?

To observe the effect of medicinal glycosides on airway inflammation chemokines and their receptors in a mouse asthma model...

2021-05-25
【Animal Modeling】-Why establish a mouse model of Alzheimer\'s disease and PRNP mutant

【Animal Modeling】-Why establish a mouse model of Alzheimer\'s disease and PRNP mutant

Alzheimer\'s disease is one of the dementias that damage human nerves caused by β-amyloid, and there is no cure for it....

2021-05-25
【Animal Modeling】-How to establish hepatitis B virus infection model in vivo and in vitro

【Animal Modeling】-How to establish hepatitis B virus infection model in vivo and in vitro

The application of different types of HBV infection models in vivo and in vitro has greatly promoted the research of HBV biological characteristics, infection process, pathogenic mechanism, etc., as well as the development and evaluation of anti-HBV ...

2021-05-25
【Animal Modeling】-How to establish a rabbit model of limited photocell degeneration in a single eye?

【Animal Modeling】-How to establish a rabbit model of limited photocell degeneration in a single eye?

Retinitis Pigmentosa (RP) is a degenerative disease of the retina that can cause night blindness and eventually lead to loss of peripheral and central vision...

2021-05-25
【Animal Modeling】-How to establish a human-derived NOD/SCID mouse model of triple-negative breast cancer?

【Animal Modeling】-How to establish a human-derived NOD/SCID mouse model of triple-negative breast cancer?

Establish a NOD/SCID mouse model with human immunological characteristics and observe its immune response to triple-negative breast cancer...

2021-05-24
【Animal Modeling】-How does diethylnitrosamine induce a liver cancer model?

【Animal Modeling】-How does diethylnitrosamine induce a liver cancer model?

Liver cancer is one of the main threats to human health and ranks second in tumor mortality. The development of primary liver cancer is the result of multiple causes and multiple stages of hepatitis-liver cirrhosis-early liver cancer-advanced liver c...

2021-05-24
【Animal Modeling】-How to establish a model of microbone granule replantation after lumbar lamina fenestration?

【Animal Modeling】-How to establish a model of microbone granule replantation after lumbar lamina fenestration?

Establish a rabbit model of bone replantation after opening the window of the rabbit lumbar vertebral lamina to provide clinical experimental basis...

2021-05-24
【Animal Modeling】-What is a cell humanized animal model?

【Animal Modeling】-What is a cell humanized animal model?

Laboratory animals are important tools and supporting platforms for life science and biomedical research and development...

2021-05-24
【Animal Modeling】-What are the principles for making animal models of human diseases?

【Animal Modeling】-What are the principles for making animal models of human diseases?

  The ultimate goal of establishing a disease model is to prevent and treat human diseases. Therefore, the reliability of the results of the disease model research depends on the similarity or equivalence between the model and human diseases....

2021-05-24
【Animal Modeling】-How to prepare a chronic rejection model of liver transplantation?

【Animal Modeling】-How to prepare a chronic rejection model of liver transplantation?

Chronic rejection mostly occurs several months after liver transplantation. It has been reported that it appears in the first month after transplantation. It is gradually aggravated and liver function gradually deteriorates. Generally, it shows irrev...

2021-05-24
【Animal Modeling】-How does the polarization type of macrophages affect the animal model?

【Animal Modeling】-How does the polarization type of macrophages affect the animal model?

Specific fibrotic diseases of the whole body and human organs are one of the most serious health problems in the world, and the mortality rate accounts for most of the world\'s population...

2021-05-24
[Animal modeling]-Primary immune thrombocytopenic purpura fever model?

[Animal modeling]-Primary immune thrombocytopenic purpura fever model?

Establish a peripheral blood thrombocytopenia model that conforms to the traditional Chinese medicine \"Heatchen syndrome\" and primary immune thrombocytopenic purpura...

2021-05-24