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【Disease Animal Model】-Traditional Induced Hepatitis C Virus Animal Model

【Disease Animal Model】-Traditional Induced Hepatitis C Virus Animal Model

The currently used HCV animal models mainly include chimpanzee hepatitis C model, tree sh hepatitis C model and rat hepatitis C model...

2021-03-10
【Disease animal model】-Traditional animal model of induced hepatitis B virus

【Disease animal model】-Traditional animal model of induced hepatitis B virus

At present, the animal models of hepatitis B virus mainly include tree sh hepatitis B model, duck hepatitis B model, marmot hepatitis B model and mouse hepatitis B model...

2021-03-10
【Disease animal model】-Pituitrin-induced angina pectoris animal model

【Disease animal model】-Pituitrin-induced angina pectoris animal model

Pituitary prostaglandin can severely contract the coronary arteries, cause acute dysfunction of the blood supply of myocardial tissue, increase peripheral resistance, increase the burden on the heart, myocardial ischemia, hypoxia, and even necrosis, ...

2021-03-09
【Disease animal model】-Electric cauterization and freezing method myocardial infarction animal model

【Disease animal model】-Electric cauterization and freezing method myocardial infarction animal model

The same belongs to the open thoracic surgery method. The difference between electrocoagulation of coronary arteries and ligation methods is that electrocoagulation blocks the coronary arteries, and the current causes local myocardial tissue necrosis...

2021-03-09
[Disease animal model]-Spontaneous coronary atherosclerotic heart disease animal model

[Disease animal model]-Spontaneous coronary atherosclerotic heart disease animal model

Myocardial infarction-type Watanabe rabbits are based on the WHHL rabbits with coronary atherosclerosis tendency, through continuous artificial selection of high plasma cholesterol levels, severe coronary atherosclerosis lesions, and the main disease...

2021-03-09
[Disease animal model]-Norepinephrine-induced rabbit cardiomyopathy model

[Disease animal model]-Norepinephrine-induced rabbit cardiomyopathy model

Injecting large amounts of norepinephrine into rabbits will increase myocardial load, myocardial degeneration and necrosis, and may cause DCM and congestive heart failure...

2021-03-09
[Disease animal model]-Spontaneous cardiomyopathy animal model

[Disease animal model]-Spontaneous cardiomyopathy animal model

The BIO14.6 hamster spontaneous cardiomyopathy model has been used for more than 30 years...

2021-03-09
【Disease animal model】-Mediastinal nerve atrial tachycardia model

【Disease animal model】-Mediastinal nerve atrial tachycardia model

The medial nerve is a mixed nerve plexus, including the parasympathetic preganglionic nerve, sympathetic afferent nerve and limb afferent nerve...

2021-03-09
【Disease animal model】-vagus atrial fibrillation model

【Disease animal model】-vagus atrial fibrillation model

Studies have shown that the vagus nervous system may be involved in the formation and maintenance of atrial fibrillation, especially related to pulmonary venous atrial fibrillation...

2021-03-09
[Disease animal model]-rapid atrial pacing atrial fibrillation model

[Disease animal model]-rapid atrial pacing atrial fibrillation model

The rapid atrial pacing atrial fibrillation model is currently the most studied and most widely used animal model of chronic atrial fibrillation...

2021-03-09
[Disease animal model]-Myocardial ischemia and myocardial infarction animal model

[Disease animal model]-Myocardial ischemia and myocardial infarction animal model

Methods to replicate animal myocardial ischemia and myocardial infarction models include ligation of coronary arteries and some left circumflex coronary arteries, most of which ligate the anterior descending branch of the left coronary artery...

2021-03-09
【Disease Animal Model】-Arrhythmia Model

【Disease Animal Model】-Arrhythmia Model

Arrhythmia can be reproduced in the whole animal, or perfused in vitro by in vitro perfusion of the isolated heart or specific parts of the heart, depending on various experimental purposes...

2021-03-09
【Disease Animal Model】-Atherosclerosis Model

【Disease Animal Model】-Atherosclerosis Model

High-cholesterol and high-fat feed method: At present, it is a more commonly used method, which has the characteristics of low mortality and long-term observation, but it is time-consuming. Usually, rabbits, pigeons, chickens, etc. can cause obvious ...

2021-03-09
【Disease animal model】-all gene knockout mice

【Disease animal model】-all gene knockout mice

Whole gene knockout is to replace the target gene with a foreign DNA sequence (in most cases, the neomycin resistance gene used for drug screening), so as to achieve the purpose of inactivating the target gene...

2021-03-08
【Disease animal model】-H7N9 avian influenza virus mouse infection animal model

【Disease animal model】-H7N9 avian influenza virus mouse infection animal model

Mice were randomly divided into normal saline control group, high, medium, and low infection dose groups according to their body weight. Each group was 10 mice and were inoculated with 1×108, 1×107 or 1×106 TCID50 virus to observe clinical symptoms a...

2021-03-08
[Disease animal model]-rat model of high altitude polycythemia

[Disease animal model]-rat model of high altitude polycythemia

Altitude sickness (called \"altitude sickness\") is a chronic altitude sickness caused by excessive red blood cell proliferation (excessive red blood cell proliferation) caused by high altitude hypoxia...

2021-03-08