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【Animal Modeling】-The effect of low molecular weight heparin on the endometrial receptivity of mice with blastocyst implantation disorder through EGFR/PI3K/Akt signaling pathway

【Animal Modeling】-The effect of low molecular weight heparin on the endometrial receptivity of mice with blastocyst implantation disorder through EGFR/PI3K/Akt signaling pathway

Apply low molecular weight heparin to treat mouse blastocyst implantation dysfunction, observe the changes of EGFR/PI3K/Akt signaling pathway, and explore its mechanism of endometrial receptivity...

2021-02-19
【Animal Modeling】-Glioblastoma nanomedicine penetrates into mouse brain to eradicate recurrent brain cancer

【Animal Modeling】-Glioblastoma nanomedicine penetrates into mouse brain to eradicate recurrent brain cancer

A new study from the University of Michigan shows that a new synthetic protein nanoparticle can slide across the almost impermeable blood-brain barrier in mice, and can deliver cancer-killing drugs directly to malignant brain tumors...

2021-02-19
[Animal Modeling]-Effect of Astragalus Polysaccharides on Growth Performance, Blood Physiological and Biochemical Indexes and Incidence of Diarrhea in Reproductive Macaques

[Animal Modeling]-Effect of Astragalus Polysaccharides on Growth Performance, Blood Physiological and Biochemical Indexes and Incidence of Diarrhea in Reproductive Macaques

To study the application of diarrhea polysaccharides in the feeding and management of experimental animals from the growth potential of diarrhea polysaccharides, blood physiology and biochemistry and the incidence of reproductive macaque diarrhea...

2021-02-19
【Animal Modeling】-The application of lactose-free milk powder with deep hydrolysis of protein in the cultivation of sterile rats

【Animal Modeling】-The application of lactose-free milk powder with deep hydrolysis of protein in the cultivation of sterile rats

When cultivating sterile rats, artificial milk given after birth is very important for cultivating sterile rats. Deeply hydrolyzed lactose-free protein milk powder is easily absorbed by infants and reduces various indigestion and allergic reactions....

2021-02-19
【Animal Modeling】-Isoliquiritin improves the inflammatory response of mice with acute kidney injury induced by cisplatin through Smad3/Arid2-IR/NF-κB axis

【Animal Modeling】-Isoliquiritin improves the inflammatory response of mice with acute kidney injury induced by cisplatin through Smad3/Arid2-IR/NF-κB axis

To study the effect of isoquinoxaline (ISO) on cisplatin-induced acute kidney injury (AKI) in mice, and explore its potential regulatory mechanism...

2021-02-19
[Animal modeling]-Serum metabonomics study of isoprenaline-induced cardiac hypertrophy in rats

[Animal modeling]-Serum metabonomics study of isoprenaline-induced cardiac hypertrophy in rats

Search for important biomarkers through serum metabolomics to study the cause of myocardial hypertrophy in rats...

2021-02-19
[Animal modeling]-Intervention of electroacupuncture on activation of dorsal root ganglion satellite glial cells and P2X7 receptor expression in rats with inflammatory pain

[Animal modeling]-Intervention of electroacupuncture on activation of dorsal root ganglion satellite glial cells and P2X7 receptor expression in rats with inflammatory pain

Activate by activating the mechanical pain threshold (foot retraction threshold, PWT) and dorsal root ganglia (DRG) of the satellite glial cells and their P2X7 receptors on the soles of rats with chronic inflammatory pain...

2021-02-19
【Animal Modeling】-The effect of placing time of arteriovenous blood cell suspension on blood routine measurement in mice

【Animal Modeling】-The effect of placing time of arteriovenous blood cell suspension on blood routine measurement in mice

Observe the effect of storage time of venous blood cell suspension on routine blood routine of mice...

2021-02-19
[Animal Modeling]-Effect of Naoshuantong Capsule on Blood Lipid Level in Atherosclerotic Mice

[Animal Modeling]-Effect of Naoshuantong Capsule on Blood Lipid Level in Atherosclerotic Mice

Observe the effect of Naoshuantong Capsule on blood lipid levels in atherosclerotic mice, and explore the therapeutic effect of Naoshuantong Capsule on stroke...

2021-02-19
【Animal Modeling】-The impact of unexpected stress stimulation on the immunity and microbial flora of the rat digestive tract

【Animal Modeling】-The impact of unexpected stress stimulation on the immunity and microbial flora of the rat digestive tract

By observing unpredictable stress stimuli in rats after 9 days of intervention, analyze the impact of unpredictable stress stimuli on the immune system of the gastrointestinal tract and microbial populations, and provide reference materials for the s...

2021-02-19
Scientists have developed a new method to generate hematopoietic stem cells with continuous energy

Scientists have developed a new method to generate hematopoietic stem cells with continuous energy

Recently, in a research report published in the international journal Cell Reports, scientists from the Spanish Genome Regulatory Center and Columbia University have identified a special kind that is essential for the expansion of scarce and life-sav...

2021-02-17
Hematopoietic stem cells improve immune response by maintaining memory of previous infections

Hematopoietic stem cells improve immune response by maintaining memory of previous infections

In a new study, researchers from France, Germany, and Israel discovered a surprising property of hematopoietic stem cells: They not only ensure the continuous renewal of blood cells, but also remember the previous infection experience, which will tri...

2021-02-17
Heavy! Scientists have developed a new strategy that can promote healthier hematopoietic stem cells!

Heavy! Scientists have developed a new strategy that can promote healthier hematopoietic stem cells!

Hematopoietic stem cells (HSCs) located in the bone marrow can produce all the blood cells of the body, including key immune cells that can protect the body against bacterial and viral infections. As the body ages, HSCs will become no longer effectiv...

2021-02-17
MAIT cell activation enhances the immunogenicity of adenovirus vector vaccine

MAIT cell activation enhances the immunogenicity of adenovirus vector vaccine

Mucosal-associated invariant T cell (Mucosal-associated invariant T cell, MAIT) is a subgroup of T cells that is important for mucosal homeostasis...

2021-02-16
Reveal that the protein NRLP1 specifically recognizes double-stranded RNA to detect the mechanism of viral infection

Reveal that the protein NRLP1 specifically recognizes double-stranded RNA to detect the mechanism of viral infection

In a new study, Veit Hornung of the University of Munich, Germany, and his team confirmed that a protein called NRLP1 found in skin cells can recognize specific nucleic acid intermediates formed during virus replication...

2021-02-16
New research maps the development of inhibitory neuronal circuits in the cerebral cortex

New research maps the development of inhibitory neuronal circuits in the cerebral cortex

How to build a neural network that is more complex than anything currently known? In a new study, researchers from the Max Planck Institute for Brain Research in Germany mapped out the developmental map of inhibitory neuronal circuits and reported th...

2021-02-16