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New ideas for enhancing the body\'s immune memory to reduce cancer recurrence rate

New ideas for enhancing the body\'s immune memory to reduce cancer recurrence rate

Scientists from the University of Pittsburgh and other institutions stated in the latest research report published in the International Journal of Natural Immunity that blocking the \"immune memory checkpoints\" identified in immune cells m...

2020-10-07
What are the mechanisms by which gut microbes affect the safety and effectiveness of drugs?

What are the mechanisms by which gut microbes affect the safety and effectiveness of drugs?

Researchers at Princeton University have developed a systematic method to assess how the gut microbiota chemically transforms or metabolizes oral drugs, thereby affecting their safety and effectiveness...

2020-10-07
Use mini organoids to study how SARS-CoV-2 destroys the human body and causes death!

Use mini organoids to study how SARS-CoV-2 destroys the human body and causes death!

SARS-CoV-2 is a virus that can destroy lung, liver and kidney tissues grown in the laboratory and may explain the serious complications of COVID-19 in the human body...

2020-10-07
In vivo studies confirmed that CAR-T cells targeting CD123 strongly inhibit normal hematopoietic function

In vivo studies confirmed that CAR-T cells targeting CD123 strongly inhibit normal hematopoietic function

Previous studies have shown that the use of CD33 and CD123 redirected CAR-T cells to treat AML has shown effective anti-leukemia activity and is in the pre-clinical and late stages of clinical development...

2020-10-07
The use of TCR-T cells expressing FOXP3 protein to treat type 1 diabetes is close to clinical

The use of TCR-T cells expressing FOXP3 protein to treat type 1 diabetes is close to clinical

Dr. Davidollings, director of the Seattle Children’s Institute of Immunotherapy Center, dreams of developing a treatment for children with type 1 diabetes for most of the past decade...

2020-10-07
New study finds that the risk of infection is highest within 30 days after CAR-T cell immunotherapy

New study finds that the risk of infection is highest within 30 days after CAR-T cell immunotherapy

According to a new study, among children and adolescents who received CD19 chimeric antigen receptor (CAR) T cell (CAR-T) injections, the infection rate increased in the first month after treatment and then decreased...

2020-10-07
Glioblastoma can be treated with CAR-T cells targeting CD133

Glioblastoma can be treated with CAR-T cells targeting CD133

When used in mice with human glioblastoma, CAR-T cell therapy targeting CD133 appears to be successful because it reduces the tumor burden in these mice and increases them...

2020-10-07
Are mesenchymal stem cells really promising to treat COVID-19?

Are mesenchymal stem cells really promising to treat COVID-19?

In a recent preliminary study conducted in China, 7 COVID-19 patients received intravenous injections of donor mesenchymal stem cells (MSCs)-pluripotent cells, which are believed to have immunomodulatory effects, as a result of this intervention Show...

2020-10-07
Discover a new mechanism for cancer cell resistance to swallow dead cancer cells and survive!

Discover a new mechanism for cancer cell resistance to swallow dead cancer cells and survive!

Drug resistance has always been the main challenge we face in the fight between humans and cancer. In the latest research report published in the international journal Nature Communications, scientists at the University of California and other instit...

2020-09-30
Clinical studies have shown that CAR-T cell therapy can improve the quality of life of DLBCL patients

Clinical studies have shown that CAR-T cell therapy can improve the quality of life of DLBCL patients

CAR-T cells can not only extend the survival period of cancer patients, but also improve the quality of life after treatment...

2020-09-30
CAR-T cell therapy targeting TGF-β has the potential to treat solid tumors

CAR-T cell therapy targeting TGF-β has the potential to treat solid tumors

Yvonne Chen, associate professor at the University of California, Los Angeles and member of the Johnson Comprehensive Cancer Center, genetically modified immune cells such as T cells to attack the most evasive enemy: cancer...

2020-09-30
A new study shows that CD229CAR-T cells are expected to treat multiple myeloma

A new study shows that CD229CAR-T cells are expected to treat multiple myeloma

Most cancer patients, such as multiple myeloma, will relapse after treatment. This harsh reality has led scientists to seek new cancer cell targeting mechanisms to improve the depth and tolerance of multiple myeloma treatments...

2020-09-30
New method promotes the survival and proliferation of CAR-T cells in solid tumors

New method promotes the survival and proliferation of CAR-T cells in solid tumors

Tumors create an unfavorable environment for immune cells (such as T cells) that fight cancer...

2020-09-30
CAR-T cell therapy edited with CRISPR-Cas9 can be used to treat refractory cancer

CAR-T cell therapy edited with CRISPR-Cas9 can be used to treat refractory cancer

According to the latest data released by researchers at the Abramson Cancer Center of the University of Pennsylvania, CAR-T cells that have undergone Crispr-Cas9 gene editing can persist in cancer patients for several months, and can stably prolifera...

2020-09-30
CRISPR gene-edited CAR-T cells are safe for cancer patients

CRISPR gene-edited CAR-T cells are safe for cancer patients

In a new study, researchers from the University of Pennsylvania and Stanford University combined two state-of-the-art methods-CRISPR (DNA editing) and T cell therapy (using immune system sentinels to destroy tumors)...

2020-09-30
Clinical trials show that gene therapy of hematopoietic stem cells is expected to treat X-chain chronic granulomatous disease

Clinical trials show that gene therapy of hematopoietic stem cells is expected to treat X-chain chronic granulomatous disease

X-chain chronic granulomatous disease (X-chain chronic granulomatous disease, X-CGD) is a rare inherited blood disease...

2020-09-30