[Animal experiment]-Scratching the skin can cause an allergic reaction to food in the intestines

Studies on mice have shown that scratching the skin triggers a series of immune responses, which eventually leads to more mast cells (immune cells involved in allergic reactions) in the small intestine being activated...

2020-09-10

[Animal Modeling]-Hemagglutinin reduces cognitive dysfunction after focal cerebral ischemia-reperfusion injury in rats

Cognitive dysfunction is the main cause of poor quality of life in stroke patients, and stroke is notorious for its high morbidity, disability, mortality and recurrence rate...

2020-09-10

【Animal Modeling】-The effect of sugar drink intake on rat heart function

Obesity is a global epidemic, and obesity-related complications such as type 2 diabetes (T2D) and cardiovascular disease (CVD) are increasing...

2020-09-10

[Animal modeling]-Blood pressure drugs are expected to treat Parkinson\'s disease and dementia in animal research

In a study conducted on mice and zebrafish at the University of Cambridge, prescription drugs used to treat Cambridge hypertension showed the potential for Parkinson’s disease, Huntington’s disease and dementia...

2020-09-10

[Animal experiment]-Gene-based factor VIIa can prevent bleeding in hemophilia animals

Hematology researchers have further improved their views on how to use current emergency treatments for controlling bleeding in patients with hemophilia as preventive treatments...

2020-09-10

【Animal Modeling】-The effect of metformin on the respiratory system of obese mice with malnutrition after birth

At present, metformin or metformin hydrochloride is considered the first choice for the treatment of type 2 diabetes...

2020-09-10

[Animal experiment]-Observation of neurotoxic effects of flame retardant TCPP on mice and related mechanism research

To study the neurotoxicity of flame-retardant TCPP (tris(2~chloroisopropyl) phosphate) on mice and its related mechanisms...

2020-09-10

[Animal modeling]-Intervention effect and mechanism of down-regulation of miR-192 on renal interstitial fibrosis in rats with unilateral ureteral obstruction

To investigate the effect of down-regulation of miR-192 expression on renal interstitial fibrosis in rats with unilateral urinary tract obstruction (UUO) and its mechanism...

2020-09-10

【Animal Modeling】-Coptis Rhizoma Polysaccharides Reduce Kidney Injury in Diabetic Rats by Inhibiting Oxidative Stress and Inflammation

To study the protective effect and potential mechanism of Rhizoma Coptidis polysaccharide on nephropathy in diabetic rats...

2020-09-10

[Animal Modeling]-Application of Nile Red Tracer Nanoformulation in In vivo Imaging of Tumor-bearing Nude Mice

How to wrap Nile Red in nano-specimen and use its fluorescence characteristics to study the tumor targeting of tumor-bearing mice and the tissue distribution of nano-specimen?...

2020-09-10

[Animal Modeling]-Can flip coins replace animal experiments?

Researchers in Berlin, Germany, did not repeat experiments on mouse disease models in the laboratory, but instead used Cointos to see if the drug could protect the brain from stroke...

2020-09-10

【Animal Modeling】-The effect of high-fat food and K/BxN serum on the immune system of ApoE knockout mice

To detect the effects of high-fat diet and K/BxN serum on the distribution of immune cells in ApoE knockout (ApoE-/-) mice...

2020-09-10

[Animal Modeling]-Effect of Astragalus on Endoplasmic Reticulum Stress Response in Vascular Remodeling in Hypertensive Rats

To study the effect of Astragalus on endoplasmic reticulum stress response in vascular remodeling in hypertensive rats, and to explore the molecular mechanism of its vascular protection?...

2020-09-10

[Animal Modeling]-The protective effect of curcumin on renal fibrosis in a mouse model of chronic kidney disease induced by 5/6 kidney ligation

To study the protective effect of curcumin on renal fibrosis in chronic kidney disease (CKD) and explore the possible mechanism?...

2020-09-10

【Animal Modeling】-The effect of dexmedetomidine on rat sciatic nerve

Peripheral nerve block is often used for postoperative pain and surgical anesthesia. Long-acting local anesthetics have an analgesic effect of 9-14 hours....

2020-09-10

[Animal Modeling]-The antidepressant effect of coumarin on chronic unpredictable mild stress mice

How to observe the antidepressant effect of Kieran and explore its possible mechanism in advance?...

2020-09-10