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In the planning and project approval of laboratory animal facilities, in addition to following the above basic principles, the following requirements should also be fully considered from the planning stage....
2020-07-24Losedcolony is a group of animals with different genotypes, also known as inbred species. This refers to a group of experimental animals that are reproduced and produced by hybrids without introducing new animals from outside. Individual circumstance...
2020-07-24Inbreeding refers to the mating of all siblings in 20 consecutive generations. All individuals in succession can be traced back to paired common ancestors that have appeared since 20 generations. After more than 20 consecutive parents and offspring h...
2020-07-24From a genetics point of view, laboratory animals are genetically restricted animals. According to different genetic characteristics, the experimental animals are divided into inbred, closed and hybrid groups. According to the degree of homozygous ge...
2020-07-24According to reports, the pig retina contains a large number of mitochondria. Since there are few reports of large mitochondria in mammalian photoreceptors, scanning electron microscopy (SEM) was used to evaluate the morphology of pig, rabbit, and mo...
2020-07-24Objective To evaluate the effects of ethanol, isopropanol, acetone and dimethyl sulfoxide on zebrafish embryonic development, especially eye development, and to provide references for its application in the study of zebrafish eye disease models....
2020-07-24
Pigs are considered to be an important host or \"mixing container\" for the production of pandemic influenza viruses. Systematic surveillance of swine flu viruses is essential for early warning and prevention of the next pandemic....
2020-07-24Objective: To establish acute and chronic hyperuricemia models in rats, use positive drugs to verify the sclerosis of the two models, and provide model tools for the development of anti-hyperuric acid drugs....
2020-07-23Simulating human aging: Ideally, all biomedical research related to humans should be conducted in humans, but due to many ethical and technical considerations, this is obviously unrealistic. Therefore, it is necessary to model human aging in non-huma...
2020-07-23
\\\"Demyelination diseases, such as multiple sclerosis and leukocyte dystrophy, are characterized by the destruction of the protective myelin sheath surrounding axons. This demyelination phenomenon may be due to autoimmune reactions or the myeli...
2020-07-23In the field of medical and biological research, especially in the safety assessment of tumors, immunity, drugs, biologics, and preclinical screening of effective drugs, NudeMouse (\"naked mice\") has always been an indispensable experiment...
2020-07-23Spinal cord injury (SCI) is caused by the displacement of herniated bone fragments in the vertebral body or spinal canal, causing varying degrees of damage to the spinal cord or cauda equina, as well as changes in motor, sensory and sphincter functio...
2020-07-23
Reviewing the data collected from the review and the summary of Table 11 at the end of the review, we can see that the choice of the appropriate system is different, as long as the metabolism of the compound under consideration involves different enz...
2020-07-23
Zika virus (ZIKV) infection is a major public health problem in the world. The World Health Organization has declared Zika virus a “public health emergency of international concern”. In 2015, Zika disease broke out in Brazil, where a large number of ...
2020-07-23Type 1 (HSV-1) and type 2 (HSV-2) herpes simplex virus (HSV) infections are the most common human infections. The herpes simplex virus usually causes self-limiting oral and genital bullous ulcers that often recur. However, HSV can cause more serious ...
2020-07-23Although the national epidemic gradually disappeared, the epidemic in Beijing \"rebounded\" and affected the hearts of people across the country. During active screening, several asymptomatic carriers were found. This must have taught us al...
2020-07-23