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【Animal Model】-Effect of chronic administration of corticosterone on depression-like behavior and synaptophysin in mice

【Animal Model】-Effect of chronic administration of corticosterone on depression-like behavior and synaptophysin in mice

To observe the effects of corticosterone on depressive-like behavior and hippocampal synaptophysin in animals by chronic administration of corticosterone...

2023-10-27
【Animal Modeling】-Research on the Necessity of Introducing the Adaptation Period to the Mouse Living Cage Experiment

【Animal Modeling】-Research on the Necessity of Introducing the Adaptation Period to the Mouse Living Cage Experiment

To explore whether the adaptation period needs to be introduced in the living cage experiment used for the detection of metabolic function of mice, and how to judge and set the length of the adaptation period...

2023-10-26
【Animal Modeling】-Israeli researchers create mouse embryo model with mouse stem cells

【Animal Modeling】-Israeli researchers create mouse embryo model with mouse stem cells

  In a new issue of the US journal Cell, Israeli researchers say they have used mouse stem cells to create a mouse embryonic model with an early brain and beating heart, a process that does not require sperm-egg fusion.   The researchers used mous...

2023-10-26
【Animal Modeling】-Making a Rabbit Myocardial Infarction Model with Minimally Invasive Cardiac Catheterization

【Animal Modeling】-Making a Rabbit Myocardial Infarction Model with Minimally Invasive Cardiac Catheterization

To investigate the myocardial infarction model in rabbits created by occlusion of coronary artery by cardiac catheterization...

2023-10-26
[Animal modeling] - The therapeutic effect of rapamycin on primary sclerosing cholangitis induced by DDC in mice

[Animal modeling] - The therapeutic effect of rapamycin on primary sclerosing cholangitis induced by DDC in mice

To investigate the therapeutic effect of rapamycin on primary sclerosing cholangitis (PSC) induced by 3,5-diethylcarbonyl 1,4-dihydrochloride in mice and its potential mechanism...

2023-10-26
[Animal Modeling ]- Animal Model of Lung Qi Deficiency Syndrome with Lipopolysaccharide and Smoking Method

[Animal Modeling ]- Animal Model of Lung Qi Deficiency Syndrome with Lipopolysaccharide and Smoking Method

Adult rats were injected with lipopolysaccharide (LPS) 200 into the trachea on the 1st and 14th days, respectively μ G/200 μ L. On the 2nd to 13th and 15th to 28th mornings, smoke 5% cigarette smoke in a 72L fumigation box for 0.5 hours. Observe the ...

2023-10-23
[Animal Modeling] - Necrotizing Enterocolitis Model in Newborn Rats

[Animal Modeling] - Necrotizing Enterocolitis Model in Newborn Rats

Newborn 1-day old Wistar rat offspring, male and female, weighing 5-10g...

2023-10-23
[Animal Modeling] - Animal Model of Viral Pulmonary Heat Syndrome

[Animal Modeling] - Animal Model of Viral Pulmonary Heat Syndrome

Adult rabbits were observed for basal body temperature and conjunctival microcirculation blood flow before the experiment, and blood samples were collected from the heart to detect their whole blood viscosity, plasma viscosity, specific antibody tite...

2023-10-23
[Animal Modeling] - Peptic Ulcer Model Induced by Histamine Phosphate

[Animal Modeling] - Peptic Ulcer Model Induced by Histamine Phosphate

rats, weighing 180-260g; Medication: Histamine phosphate...

2023-10-23
[Animal Modeling ]- Stress Induced Peptic Ulcer Model

[Animal Modeling ]- Stress Induced Peptic Ulcer Model

Male SD rats, 14 weeks old, weighing 150-200g; Medication: Ether, 1% formaldehyde solution...

2023-10-23
【Animal Modeling】-Experimental Study on Establishing Rat Obesity Model with High Calorie Feed

【Animal Modeling】-Experimental Study on Establishing Rat Obesity Model with High Calorie Feed

To observe the effect of using high-calorie diet to establish an obesity model in rats, as well as the modeling differences between the two breeds of rats, and to compare different methods of evaluating obesity and screening methods of obesity-sensit...

2023-10-18
[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

To study the effects of different doses of isoproterenol on cardiac function and pathomorphology in rats...

2023-10-18
【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

To investigate the effects of different administration routes and doses of cyclophosphamide on the embryos and fetuses of pregnant rabbits, so as to determine the best administration method for inducing fetal malformation in rabbits...

2023-10-18
【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

To investigate the effect of curcumin on glucose transport and phosphatidylinositol kinase-3 (PI3K)/protein kinase B (Akt) signaling pathway in adipocytes of type 2 diabetes mellitus (T2DM) rats...

2023-10-18
[Animal modeling] - Study on the effect of Tongxinluo on the early pathological changes of calcified aortic valvular disease in mice

[Animal modeling] - Study on the effect of Tongxinluo on the early pathological changes of calcified aortic valvular disease in mice

To observe whether Tongxinluo intervention can delay the progression of calcified aortic valvular disease in the early stage...

2023-10-18
[Animal modeling] - chloroform induced arrhythmia model

[Animal modeling] - chloroform induced arrhythmia model

Kunming mice, weighing (35 ± 5) g, both male and female; Drug: chloroform; Equipment: Biological function experimental system...

2023-10-16