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[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in rats anesthetized with propofol

[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in rats anesthetized with propofol

To explore the effect of cannabinol on monoamine neurotransmitters in the central nervous system in methamphetamine dependent rats, explain the therapeutic mechanism of CBD on METH dependence, and provide reference for the development of drug depende...

2023-01-29
[Animal modeling] - Kaixinsan injected A into bilateral hippocampal CA1 area β Study on the therapeutic effect and mechanism of AD rats induced by 1-42

[Animal modeling] - Kaixinsan injected A into bilateral hippocampal CA1 area β Study on the therapeutic effect and mechanism of AD rats induced by 1-42

To investigate the effect of Kaixinsan on the injection of A into bilateral hippocampal CA1 region β The therapeutic effect of 1-42 on AD rats, and its mechanism of action is preliminarily clarified...

2023-01-29
【Animal Modeling】-Comparison of single staining and counterstaining in the observation of osteoarthritis sections of SIRT1 knockout mice

【Animal Modeling】-Comparison of single staining and counterstaining in the observation of osteoarthritis sections of SIRT1 knockout mice

To establish a related mouse knee osteoarthritis model by knocking out SIRT1 gene, and to observe the differences in the morphology of cartilage tissue sections with different single staining or compound staining techniques...

2023-01-29
【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

Osteoporosis model constructed with ovariectomized rats is the most suitable model to study postmenopausal osteoporotic disease, however, the effect on skin after ovary removal in rats is seldom studied....

2023-01-29
Research on spinal muscular atrophy achieves breakthrough through animal modeling technology

Research on spinal muscular atrophy achieves breakthrough through animal modeling technology

A few days ago, the Institute of Neuroscience of Soochow University and Professor Hua Yimin of Cold Spring Harbor Laboratory in the United States developed a number of mouse disease models, which effectively increased the expression of motor neuron s...

2023-01-18
[Animal modeling]-Infectious SIV exists in the fatty tissue of chronically infected rhesus monkeys and causes metabolic defects

[Animal modeling]-Infectious SIV exists in the fatty tissue of chronically infected rhesus monkeys and causes metabolic defects

Memory CD4 T cells and macrophages are the main host and cell bank of humans and HIV in non-human primates...

2023-01-18
【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...

2023-01-18
【Animal Modeling】-The effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

【Animal Modeling】-The effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

How to evaluate the effects of aerobic exercise and metformin combined with aerobic exercise on vascular oxidative stress in type 2 diabetic rats?...

2023-01-18
【Animal Modeling】-Applying TaqMan probe fluorescence quantitative PCR technology to identify the genotypes of Leprdb/+ mouse progeny

【Animal Modeling】-Applying TaqMan probe fluorescence quantitative PCR technology to identify the genotypes of Leprdb/+ mouse progeny

How to establish an effective method for genotyping Leprdb/+ mouse offspring using TaqMan probe fluorescence quantitative PCR technology...

2023-01-18
【Animal Modeling】-Methodological Research on Establishing Mouse Model of Learning and Memory Impairment

【Animal Modeling】-Methodological Research on Establishing Mouse Model of Learning and Memory Impairment

To study effective methods to avoid darkness and Morris water maze experiment to establish a model of learning and memory impairment in mice...

2023-01-18
【Animal Modeling】-New Model of Colon Cancer

【Animal Modeling】-New Model of Colon Cancer

MIT researchers showed in mice that a gene editing system called CRISPR can be used to generate colon tumors that are very similar to human tumors...

2023-01-18
【Animal Modeling】-Mixed Memory Disorder Model

【Animal Modeling】-Mixed Memory Disorder Model

反复脑缺血再灌法建立学习记忆障碍模型...

2023-01-18
[Animal modeling]-Different concentrations of Aβ25-35 protein to simulate Alzheimer\\\\

[Animal modeling]-Different concentrations of Aβ25-35 protein to simulate Alzheimer\\\\

After intracerebroventricular injection of different concentrations of amyloid Aβ25-35, observe the changes in the learning and memory ability of the Morris water maze in rats, determine the optimal concentration of Aβ25-35 injection for AD model rat...

2023-01-18
【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

To explore electroacupuncture on synaptic plasticity and microglia polarization in rats with focal cerebral ischemia, and to detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2023-01-17
【Animal Modeling】-Application of Intracavitary Shunt Plug in Heterotopic Abdominal Heart Transplantation in Rats

【Animal Modeling】-Application of Intracavitary Shunt Plug in Heterotopic Abdominal Heart Transplantation in Rats

  To explore the application of intravascular shunt plug in establishing heterotopic abdominal heart transplantation rat model...

2023-01-17
【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

To use 16S rRNA high-throughput sequencing method to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and to compare and analyze the oral flora o...

2023-01-17