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【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

This study was the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits in a hyperlipidemia mouse model through the measurement of lipid metabolism experimental indicators, aiming to provide a new functio...

2022-10-26
【Animal Modeling】-Study draws a map of human hematopoietic stem cells from hematopoietic endothelium to birth

【Animal Modeling】-Study draws a map of human hematopoietic stem cells from hematopoietic endothelium to birth

Researchers such as Hanna K. A. Mikkola and Vincenzo Calvanese of the University of California, Los Angeles, collaborated to map human hematopoietic stem cells from the hematopoietic endothelium to birth...

2022-10-26
【Animal modeling】-Protective effect of γ-secretase inhibitor on white matter damage in neonatal rats induced by hyperoxia exposure

【Animal modeling】-Protective effect of γ-secretase inhibitor on white matter damage in neonatal rats induced by hyperoxia exposure

To investigate the effect of γ-secretase inhibitor on white matter damage in neonatal mice induced by atmospheric pressure and high concentration oxygen exposure...

2022-10-26
【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

To establish an in vitro model of intestinal epithelial cells—small intestinal organoid culture system, and to explore its related pathological detection techniques, so as to provide a convenient platform for the in vitro research of intestinal-relat...

2022-10-26
【Animal modeling】-Effect of prostacyclin E1 on hepatic fibrosis in rabbits after hepatic arterial lipiodol embolization

【Animal modeling】-Effect of prostacyclin E1 on hepatic fibrosis in rabbits after hepatic arterial lipiodol embolization

To investigate the effect of prostacyclin E1 on the mRNA expression levels of Smad2 and Smad4 in rabbits with hepatic fibrosis after hepatic arterial lipiodol embolization...

2022-10-26
【Animal modeling】-phenotype and pathological observation of leptin receptor gene knockout SD rats

【Animal modeling】-phenotype and pathological observation of leptin receptor gene knockout SD rats

To observe various parameters of the leptin receptor gene knockout rat model of obesity, metabolic syndrome and prediabetes established by CRISPR/Cas9 technology, and to provide a more ideal basis for the molecular mechanism research of metabolic dis...

2022-10-26
【Animal modeling】-Mechanism of transient receptor potential channel C1 in airway remodeling in guinea pig asthma and the intervention effect of budesonide

【Animal modeling】-Mechanism of transient receptor potential channel C1 in airway remodeling in guinea pig asthma and the intervention effect of budesonide

To explore the mechanism of TRPC1 ion channel in the evolution of airway remodeling and the intervention effect of budesonide by interfering with the expression of transient receptor potential channel C1 (TRPC1)...

2022-10-26
How to construct animal models of type II diabetes in rats and mice?

How to construct animal models of type II diabetes in rats and mice?

How to construct animal models of type II diabetes in rats and mice? This question has been asked by many netizens, so today Zhonghong Boyuan will give you a technical sharing....

2022-10-26
[Animal Modeling]-Mouse stem cells can form \\\\\\\"embryonic\\\\\\\" structures in vitro

[Animal Modeling]-Mouse stem cells can form \\\\\\\"embryonic\\\\\\\" structures in vitro

A team of European scientists published a medical paper in the British journal Nature, claiming that they only used mouse stem cells to cultivate structures similar to early embryos in petri dishes....

2022-10-26
【Animal modeling】-Effect of dexmedetomidine on renal function and tight junction protein expression in septic rats

【Animal modeling】-Effect of dexmedetomidine on renal function and tight junction protein expression in septic rats

To investigate the effect of dexmedetomidine on renal function and tight junction protein expression in septic rats...

2022-10-26
【Animal Modeling】-Skin cells come from genetically modified pigs

【Animal Modeling】-Skin cells come from genetically modified pigs

Recently, the US Food and Drug Administration (FDA) approved XenoTherapeutics to initiate the first clinical trial of xenotransplantation...

2022-10-26
【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

To investigate the possibility of cabozantinib, a c-Met receptor tyrosine kinase inhibitor, as a novel drug against Listeria monocytogenes infection...

2022-10-24
【Animal Modeling】-Study on changes in the number and traits of cardiac fibroblasts in early postnatal mice

【Animal Modeling】-Study on changes in the number and traits of cardiac fibroblasts in early postnatal mice

Cardiac fibroblasts account for more than 50% of cardiac cells and play an important role in cardiac physiology and pathology. The 7th day after birth is a turning point when the heart loses its ability to regenerate. This study aimed to study the ch...

2022-10-24
【Animal modeling】-Protective effect of atorvastatin on joint injury in ApoE-/- mice

【Animal modeling】-Protective effect of atorvastatin on joint injury in ApoE-/- mice

To observe the protective effect of atorvastatin on joint injury in ApoE-/- mice...

2022-10-24
【Animal Modeling】-Icariin on the Androgen Receptor Signaling Pathway in SCID Mice Prostate Cancer Orthotopic Transplantation Tumor

【Animal Modeling】-Icariin on the Androgen Receptor Signaling Pathway in SCID Mice Prostate Cancer Orthotopic Transplantation Tumor

How to observe the effect of icariin on the androgen receptor signaling pathway in prostate cancer orthotopic xenografts in SCID mice?...

2022-10-24
[Animal Modeling]-Brain immune memory affects neurological disease progression in mice

[Animal Modeling]-Brain immune memory affects neurological disease progression in mice

The immune response in mice affects the severity of late-stage brain diseases in mice through immune memory...

2022-10-24