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【Animal Modeling】-Using Orthogonal Test to Optimize the Establishment of a Rat Conditioned Fear Memory Model

【Animal Modeling】-Using Orthogonal Test to Optimize the Establishment of a Rat Conditioned Fear Memory Model

To optimize the optimal experimental parameters for establishing a conditioned fear memory model in rats by using orthogonal experiments, and to find the optimal experimental conditions...

2022-09-13
【Animal Modeling】-Analysis of Mozart\'s K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

【Animal Modeling】-Analysis of Mozart\'s K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

To establish a depression model in C57BL/6 mice, and to preliminarily explore the effect of high-frequency sound waves in Mozart\'s K448 sonata on improving depressive symptoms in C57BL/6 mice...

2022-09-13
【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

To select a human hepatoma cell line (HCCLM3-Luc) stably expressing a luciferase reporter gene, and to construct an in situ tumor-bearing nude mouse model of human hepatoma cell line...

2022-09-13
【Animal modeling】-Establishment of an inflammatory model of BALB/c mice infected with influenza A virus

【Animal modeling】-Establishment of an inflammatory model of BALB/c mice infected with influenza A virus

To analyze the pathogenicity of influenza A virus using a mouse model of inflammation...

2022-09-13
【Animal Modeling】-Comparison of Two Hepatitis B Hepatitis B Fibrosis Mouse Compound Models

【Animal Modeling】-Comparison of Two Hepatitis B Hepatitis B Fibrosis Mouse Compound Models

To use C57BL/6N-Tg(1.28HBV)/Vst hepatitis B virus transgenic mice and rAAV8-1.3HBV adeno-associated virus-transfected mice combined with CCl4 intraperitoneal injection to induce hepatitis B fibrosis mouse model, and compare the two mice Virological a...

2022-09-13
【Animal modeling】-Establishment and significance of nerve electrophysiological detection model during dorsal penile neurectomy in Beagle dogs

【Animal modeling】-Establishment and significance of nerve electrophysiological detection model during dorsal penile neurectomy in Beagle dogs

To investigate the detection method of penile somatosensory evoked potentials in beagle dogs under general anesthesia and the changes of somatosensory evoked potentials in the process of dorsal penile nerve resection, so as to provide reference for f...

2022-09-13
【Animal modeling】-Establishment of acute and chronic hyperuricemia models

【Animal modeling】-Establishment of acute and chronic hyperuricemia models

To establish acute mouse and chronic rat hyperuricemia models, and use positive drugs to verify the curability of the two models, so as to provide model tools for the development of anti-hyperuric acid drugs...

2022-09-13
【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

To comprehensively evaluate the improved method for establishing myocardial ischemia-reperfusion injury model in rats...

2022-09-13
【Animal Modeling】-Gene-modified SLE mouse model

【Animal Modeling】-Gene-modified SLE mouse model

Transgenic mouse model B6.Cg-Tg (Actb-TNFRSF6B) 754Jwu/J, gene knock-in mouse model 129S6.129X1 (B6)-Ptprctm1Weis / and many other types of transgenic mouse models for studying autoimmune diseases Have. J and B6.129X1-Ptprctm1Weis/J, gene knockout mo...

2022-09-13
【Animal Modeling】-Establishment and Evaluation of a Mouse Model of Diabetic Lower Limb Ulcer

【Animal Modeling】-Establishment and Evaluation of a Mouse Model of Diabetic Lower Limb Ulcer

To establish and evaluate a mouse model of diabetic lower extremity ulcer, reveal the changes of blood flow and pathophysiology in the operated limb of diabetic lower extremity ulcer mice, and explore its pathogenesis, so as to provide a basis and re...

2022-09-09
【Animal modeling】-Establishment and evaluation of a rat model of chronic obstructive pulmonary disease

【Animal modeling】-Establishment and evaluation of a rat model of chronic obstructive pulmonary disease

To construct a rat model of chronic obstructive pulmonary disease by smoking method, protease instillation and a combination of the two methods...

2022-09-09
【Animal Modeling】-Experimental Observation on Evaluation Points of Blood Glucose Intervention in Mice Model of Type 2 Diabetes

【Animal Modeling】-Experimental Observation on Evaluation Points of Blood Glucose Intervention in Mice Model of Type 2 Diabetes

To observe the changes of blood glucose in a mouse model of type 2 diabetes mellitus, and to explore the feasibility of 2 h postprandial blood glucose as an evaluation point for blood glucose intervention...

2022-09-09
【Animal Modeling】-Observation on Induced Anxiety and Depression-like Emotional Behavior in Chronic Inflammatory Pain Model Rats

【Animal Modeling】-Observation on Induced Anxiety and Depression-like Emotional Behavior in Chronic Inflammatory Pain Model Rats

To dynamically observe the changes of pain emotion in chronic inflammatory pain model rats induced by complete Freund\'s adjuvant (CFA), and to explore the time differences of anxiety and depression in chronic inflammatory pain model rats...

2022-09-09
【Animal Modeling】-In vitro and animal models for SARS-CoV-2 research

【Animal Modeling】-In vitro and animal models for SARS-CoV-2 research

In December 2019, China confirmed pneumonia of unknown etiology. The Chinese Center for Disease Control and Prevention (CCDC) has identified a novel coronavirus infection as the cause of the pneumonia...

2022-09-09
【Animal Modeling】-Preparation of long-term stable SD rat type 2 diabetes model

【Animal Modeling】-Preparation of long-term stable SD rat type 2 diabetes model

To explore the preparation method of high-fat diet combined with streptozotocin-induced diabetic rat model, and to provide a stable diabetic animal model for clinical research...

2022-09-08
【Animal Modeling】-Construction of Parkinson\'s Disease Cynomolgus Monkey Systemic Model and Dynamic Evaluation of In Vivo Clinical Process

【Animal Modeling】-Construction of Parkinson\'s Disease Cynomolgus Monkey Systemic Model and Dynamic Evaluation of In Vivo Clinical Process

To dynamically evaluate the clinical characteristics of Parkinson\'s disease systemic models in cynomolgus monkeys using behavioral and molecular imaging methods, and to provide a stable and effective PD primate model for preclinical research on drug...

2022-09-08