
To study the subacute inhalation toxicity of ivermectin original drug to rats, and to find the maximum ineffective dose...
2024-10-14![[Animal Modeling] - Sterile Pericarditis Model](/./uploads/images/default/default.png)
Atrial fibrillation often occurs after thoracotomy, and pericarditis is considered an important cause of atrial fibrillation...
2024-10-11![[Animal Modeling] - Exploration of Evaluation Methods for Rat Models of Phlegm Dampness Stagnation Syndrome in Premature Sexual Maturity](/./uploads/images/default/default.png)
To explore a systematic evaluation method for a rat model of precocious puberty with phlegm dampness obstruction syndrome...
2024-10-11![[Animal modeling] - The changes of dendritic cell function in white haired black eye rabbit allergic rhinitis model mediated by ovalbumin](/./uploads/images/default/default.png)
To observe the function of dendritic cells derived from peripheral blood of white haired black eyed rabbits and Japanese white rabbits with allergic rhinitis induced by ovalbumin, and to reveal the possible mechanism of WHBE rabbits\\\\\\\' sensitivi...
2024-10-08
To establish a good, fast, and stable mouse primary liver cancer model...
2024-10-08
How to establish a mouse anti-rabies virus IgG antibody ELISA detection method for the detection and analysis of rabies mouse models?...
2024-10-08
To investigate the role of mitochondria-cytochrome C pathway in the apoptosis of rabbit non-alcoholic fatty liver liver cells...
2024-10-08![[Animal modeling] - identification of a skin type lupus mouse model](/./uploads/images/default/default.png)
To observe and identify the skin symptoms of aged systemic lupus erythematosus (TC) mice and explore whether it can be used as a mouse model for studying cutaneous lupus...
2024-10-07![[Animal Modeling] - The Improving Effect of Sulindac on Symptomatic Behavior in Autism Model Rats](/./uploads/images/default/default.png)
To explore the improvement effect of sulindac on the behavior of autism model rats...
2024-10-07
New Zealand rabbit, weighing around 2.5kg. Inject 10ml of standard crude E. coli endotoxin (containing 5 × 10 of E. coli per milliliter to the 7th power) intravenously, followed by 10ml intravenously after 6-24h. After the second injection, diffuse i...
2024-09-27
Anesthetize animals with 30mg/kg pentobarbital, disinfect the skin routinely, make an incision on the left side of the abdomen, expose the left side, and peel off the renal fascia. Freeze the upper, lower, lateral anterior, and posterior parts of the...
2024-09-27![[Animal Modeling - Efficacy Evaluation] - Transgenic Mouse Infection Model](/./uploads/images/default/default.png)
Cut the fragment containing HCV 5\'UTR and structural genes (C1+E1+E2) from the pHCS plasmid by enzymatic digestion, pass it through the intermediate vector pMT, and then perform enzymatic digestion to construct a new plasmid (pCBE). After amplificat...
2024-09-26![[Animal Modeling - Pharmacological Evaluation] - Chronic Renal Failure Rat Model Induced by Xiaozhiling](/./uploads/images/default/default.png)
Model animals are first anesthetized with ketamine and diazepam, supplemented with ether inhalation if necessary. Rats were fixed in a supine position, and a 1.2ml dilution of refined Xiaozhiling injection was prepared by adding an equal amount of ph...
2024-09-26
1ml of adenine suspension was prepared at a daily dose of 200mg/kg and administered to rats by gavage at regular intervals, with a total cumulative dose of 1.5g/animal. The entire modeling process lasted for 24 days. Administer once a day from day 1 ...
2024-09-26![[Animal modeling - Drug efficacy evaluation] - Negative pressure traumatic brain injury model](/./uploads/images/default/default.png)
The negative pressure traumatic brain injury model established by Mahmood et al. mainly consists of a stent, straw, syringe tube, spring coil, pressure sensing transducer, oscilloscope, etc...
2024-09-25![[Animal Modeling - Efficacy Evaluation] - Hepatitis B Virus Infection Model](/./uploads/images/default/default.png)
Hepatitis B virus belongs to the hepatotropic DNA virus, which is a complex DNA virus. Since the 1970s, researchers have identified Dane particles (i.e. HBV particles) under electron microscopy and clarified that the surface component of HBV particle...
2024-09-25