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【Animal modeling】-In vitro co-culture of bovine blastocysts induces differential expression of integrin αv, β3 genes in endometrial epithelial cells

【Animal modeling】-In vitro co-culture of bovine blastocysts induces differential expression of integrin αv, β3 genes in endometrial epithelial cells

  Objective: Using the co-culture method of bovine embryos and endometrial epithelial cells in vitro, to explore the changes of integrin αv, β3 gene differential expression in endometrial epithelial cells before and after co-culture, in order to esta...

2022-06-08
【Animal Modeling】-Constructing severe combined immunodeficiency mice based on CRISPR/Cas9 technology

【Animal Modeling】-Constructing severe combined immunodeficiency mice based on CRISPR/Cas9 technology

To use CRISPR/Cas9 technology to target knockout of Rag2 gene encoding mouse T and B cells and IL2rg gene encoding NK cells, and to construct T, B cells and NK cells combined immunodeficiency mice...

2022-06-08
【Animal modeling】-GGTA1-/- Wuzhishan miniature pig SLA class I gene molecular characteristics and similarity analysis with HLA

【Animal modeling】-GGTA1-/- Wuzhishan miniature pig SLA class I gene molecular characteristics and similarity analysis with HLA

To clarify the molecular structure of SLA class I gene of Wuzhishan miniature pig with α-1,3 galactosyltransferase gene knockout (GGTA1-/-) and its similarity with human HLA, and to study the cellularity of xenotransplantation. Rejection is important...

2022-06-08
【Animal modeling】-Changes of biological characteristics of black-lined hamsters infected with Babesia

【Animal modeling】-Changes of biological characteristics of black-lined hamsters infected with Babesia

To establish a black-lined hamster model infected with babesiosis, to clarify the changes of biological characteristics of black-lined hamsters after infection, and to provide basic data for the detection and prevention of babesiosis...

2022-06-08
【Animal modeling】-Analysis of genetic detection of microsatellite DNA in highly immunodeficient mice from different sources

【Animal modeling】-Analysis of genetic detection of microsatellite DNA in highly immunodeficient mice from different sources

To detect and analyze the genetic background of highly immunodeficient mice from different sources, in order to find out whether the genetic background of the genetically modified mice conforms to the genetic characteristics of inbred lines...

2022-06-08
【Animal Modeling】-Comparison of Transfection Efficiency of Adenovirus Vectors by Tail Vein Injection and Myocardial Injection in Mice

【Animal Modeling】-Comparison of Transfection Efficiency of Adenovirus Vectors by Tail Vein Injection and Myocardial Injection in Mice

To compare the transfection efficiency of target genes in heart tissue and liver tissue after injection of adenovirus vector into mouse tail vein or myocardium...

2022-06-08
【Animal Modeling】-ECG Characteristics of Stress-stressed Chronic Heart Failure Rats

【Animal Modeling】-ECG Characteristics of Stress-stressed Chronic Heart Failure Rats

To detect and analyze the characteristics of stress-loaded chronic heart failure rats by electrocardiogram...

2022-06-08
【Animal Modeling】-Parasitic Infection and Drug Purification Effect of Closed Group Meridian Gerbils

【Animal Modeling】-Parasitic Infection and Drug Purification Effect of Closed Group Meridian Gerbils

To lay a foundation for the establishment of a clean-grade Meridian gerbil population, and to provide a reference for formulating the detection standard of Meridian gerbil parasites...

2022-06-08
【Animal modeling】-Analysis of clinical characteristics of mice infected with parvovirus

【Animal modeling】-Analysis of clinical characteristics of mice infected with parvovirus

To analyze the distribution law, detoxification and antibody changes of mouse parvovirus (MVM) in artificially infected mice, and the situation of mice infected with MVM under natural conditions...

2022-06-07
【Animal modeling】-Zmu-1:DHP inbred guinea pig breeding and preliminary identification of molecular genetic structure

【Animal modeling】-Zmu-1:DHP inbred guinea pig breeding and preliminary identification of molecular genetic structure

To cultivate inbred guinea pig strains and establish microsatellite molecular markers for detecting the genetic structure of guinea pigs...

2022-06-07
【Animal Modeling】-Distribution of Autofluorescent Microorganisms in Rat Intestine

【Animal Modeling】-Distribution of Autofluorescent Microorganisms in Rat Intestine

To investigate the distribution of autofluorescent microbes in the gut of rats at different developmental stages...

2022-06-07
【Animal modeling】- PERV-env gene cloning and tissue expression profiling in Guangxi Bama miniature pigs

【Animal modeling】- PERV-env gene cloning and tissue expression profiling in Guangxi Bama miniature pigs

To clone part of PERV-env gene of Guangxi Bama miniature pig, and study its expression difference in different tissues...

2022-06-07
【Animal Modeling】- Mouse spleen mesenchymal stem cells regulate the proliferation and activation of T lymphocytes

【Animal Modeling】- Mouse spleen mesenchymal stem cells regulate the proliferation and activation of T lymphocytes

To study the regulatory effect of mouse spleen mesenchymal stem cells (Sp-MSCs) on the proliferation and activation of T lymphocytes...

2022-06-07
【Animal Modeling】-Analysis of the expression levels of Rxra in six tissues of spontaneously diabetic gerbils

【Animal Modeling】-Analysis of the expression levels of Rxra in six tissues of spontaneously diabetic gerbils

To analyze the expression levels of Rxra gene in 6 tissues of diabetic gerbils, in order to explore the molecular mechanism of diabetes in gerbils...

2022-06-07
【Animal Modeling】-Establishment of a method for the detection of Helicobacter pylori in living gerbils

【Animal Modeling】-Establishment of a method for the detection of Helicobacter pylori in living gerbils

To use the nested PCR method to detect the infection of Helicobacter pylori in the gerbil in vivo by gastric juice, so as to establish a detection technology that can continuously monitor the infection of Helicobacter pylori in the gerbil...

2022-06-07
【Animal Modeling】-Isolation and Identification of Miniature Pig Japanese Encephalitis Virus for Experimental Use

【Animal Modeling】-Isolation and Identification of Miniature Pig Japanese Encephalitis Virus for Experimental Use

To understand the characteristics of Japanese encephalitis virus strains in miniature pigs...

2022-06-07