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How to establish a non-alcoholic fatty liver disease model? -Animal modeling

How to establish a non-alcoholic fatty liver disease model? -Animal modeling

Establish a new type of hyperlipidemia (WSHc) rat non-alcoholic fatty liver disease (NAFLD) model, observe the changes in blood biochemical indicators and pathological characteristics, and apply and study a sick animal model, which explores the value...

2021-12-21
How to establish an animal model of lung cancer bone metastasis? -【Animal Modeling】

How to establish an animal model of lung cancer bone metastasis? -【Animal Modeling】

Bone metastasis is one of the common complications of lung cancer. The higher the patient’s survival rate, the greater the risk of bone metastasis....

2021-12-16
Animal modeling technology shows that cytomegalovirus vaccine is effective against Ebola virus

Animal modeling technology shows that cytomegalovirus vaccine is effective against Ebola virus

In addition to proving the anti-Ebola virus effect of the cytomegalovirus vaccine, the researchers also studied its protective mechanism...

2021-12-16
【Animal Modeling】-What method is used to prepare a rat model of middle cerebral artery embolism?

【Animal Modeling】-What method is used to prepare a rat model of middle cerebral artery embolism?

Comparing the timeliness, success rate and mortality of rat middle cerebral artery embolization (MCAO) models established by common carotid artery puncture and conventional thread embolization...

2021-12-16
【Animal Modeling】-Animal Model of Metabolic Syndrome

【Animal Modeling】-Animal Model of Metabolic Syndrome

Metabolic syndrome is characterized by the occurrence of at least the following three diseases: obesity, hyperglycemia, hypertension, or dyslipidemia...

2021-12-16
Type I hereditary tyrosinemia is mainly caused by the mutation of FAH gene (fumaryl acetoacetate hydroxylase, FAH), which normalizes fumaric acid and acetoacetate. Is it the inability to metabolize ty

Type I hereditary tyrosinemia is mainly caused by the mutation of FAH gene (fumaryl acetoacetate hydroxylase, FAH), which normalizes fumaric acid and acetoacetate. Is it the inability to metabolize ty

Type I hereditary tyrosinemia is mainly caused by the mutation of FAH gene (fumaryl acetoacetate hydroxylase, FAH), which normalizes fumaric acid and acetoacetate. Is it the inability to metabolize tyrosine? Acid recessive genetic disease?...

2021-12-16
How to build an animal model of tic disorder? -Animal modeling

How to build an animal model of tic disorder? -Animal modeling

Tic disorder is a common neurodevelopmental disorder in childhood, mainly manifested as involuntary repetitive sudden movements and vocalizations...

2021-12-16
【Animal Modeling】-Establishment of a mouse model of IgA nephropathy induced by superantigen Staphylococcal enterotoxin B

【Animal Modeling】-Establishment of a mouse model of IgA nephropathy induced by superantigen Staphylococcal enterotoxin B

Establish a mouse IgA nephropathy model and observe its biochemical and pathological characteristics...

2021-12-16
【Animal Modeling】-HBV transgenic mouse model

【Animal Modeling】-HBV transgenic mouse model

Establish transgenic mice expressing part or all of the HBV genome, and study the mechanism of HBV replication, the expression of viral genes in liver cell injury, and HBV immunopathology...

2021-12-16
[Animal Modeling]-How to establish a fluorescent PCR detection method for mouse polyomavirus?

[Animal Modeling]-How to establish a fluorescent PCR detection method for mouse polyomavirus?

Establish a fluorescent quantitative PCR detection method for polyoma virus to explore the situation of naked mole mouse polyoma virus infection...

2021-12-16
[Disease animal modeling]-Rabbit electrical stimulation of the heart causes ventricular arrhythmia

[Disease animal modeling]-Rabbit electrical stimulation of the heart causes ventricular arrhythmia

New Zealand rabbits weighing about 2.5kg are anesthetized by intravenous injection of 3% sodium pentobarbital at a dose of 30mg/kg body weight, and fixed in lateral position; needle electrodes are pierced into the rabbit’s limbs and connected to the...

2021-12-15
【Animal Modeling】-Comparison of liver toxicity between matrine and oxymatrine in vitro and in vivo models

【Animal Modeling】-Comparison of liver toxicity between matrine and oxymatrine in vitro and in vivo models

Compare the liver toxicity of matrine (MT) and oxymatrine (OMT), study the severity and characteristics of its toxicity, and first clarify its toxicity mechanism?...

2021-12-15
【Animal Modeling】-Inactivated H37Rv whole bacterial sensitization model

【Animal Modeling】-Inactivated H37Rv whole bacterial sensitization model

Tuberculosis is a chronic infectious disease that is zoonotic. It is highly pathogenic and lethal worldwide and is caused by Mycobacterium tuberculosis....

2021-12-15
【Animal Modeling】-The effect of ghrelin on the expression of hippocampus DKK-1 and the function of learning and memory in diabetic rats

【Animal Modeling】-The effect of ghrelin on the expression of hippocampus DKK-1 and the function of learning and memory in diabetic rats

Observe the changes in the expression of ghrelin in DKK-1 and WNT signaling pathways in diabetic rats, and explore the mechanism of its involvement in learning and memory functions...

2021-12-15
【Animal Modeling】-Schizophrenia Model

【Animal Modeling】-Schizophrenia Model

Establish a rat model of schizophrenia, observe the pathological damage of the prefrontal cortex and the expression changes of PKA and endothelial cell chemokine-5, clarify the mechanism of nerve damage, and guide clinical treatment. Does it provide...

2021-12-15
【Animal Model】-A new model of rat artery transplantation

【Animal Model】-A new model of rat artery transplantation

Allograft vascular disease (AV) limits the function and long-term survival of transplanted organs. This is the most pressing global issue in the field of organ transplantation...

2021-12-15