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Revealing the structural mechanism of SARS-CoV-2 spike protein binding to human ACE2 receptor

Revealing the structural mechanism of SARS-CoV-2 spike protein binding to human ACE2 receptor

In a new study, researchers from the Francis-Crick Institute in the United Kingdom found that the spike protein (S protein) on the surface of the SARS-CoV-2 coronavirus can be used when it comes into contact with the human virus receptor ACE2. At lea...

2020-10-30
Tsinghua University and Zhejiang University join forces to reveal the molecular structure of the new coronavirus

Tsinghua University and Zhejiang University join forces to reveal the molecular structure of the new coronavirus

The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant around the world....

2020-10-30
Reveal the neutralization site and immunodominant site of the RBD domain of the new coronavirus S protein

Reveal the neutralization site and immunodominant site of the RBD domain of the new coronavirus S protein

The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant around the world....

2020-10-30
Chinese scientists structurally reveal that BD-368-2 antibody can effectively treat hamsters severely infected by the new coronavirus

Chinese scientists structurally reveal that BD-368-2 antibody can effectively treat hamsters severely infected by the new coronavirus

Understanding how effective neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is the key to developing effective therapies. In a previous new study, using the expertise of single-cell genomics, Peking University Beijing Advanced Innovation Center for...

2020-10-30
Analysis of the structure and function of the SARS-CoV-2 spike protein variant D614G

Analysis of the structure and function of the SARS-CoV-2 spike protein variant D614G

Since December 8, 2019, several cases of pneumonia of unknown etiology have been reported in Wuhan City, Hubei Province, China. Most patients work or live near the local Huanan Seafood Wholesale Market...

2020-10-30
Solve the three-dimensional structure of the BAF complex in human cells

Solve the three-dimensional structure of the BAF complex in human cells

A key molecular \\\"machine\\\" called the BAF complex can change the structure of DNA, and mutations often occur in cancer and other diseases...

2020-10-30
Susceptible cells may be able to protect themselves from pathogen infection by removing cholesterol on the cell surface

Susceptible cells may be able to protect themselves from pathogen infection by removing cholesterol on the cell surface

A few days ago, in a research report published in the international journal Nature Microbiology, scientists at the University of Texas Southwestern Medical Center and other institutions found that when the immune system detects danger, certain bodies...

2020-10-30
Cholesterol drugs can effectively alleviate the spread of breast cancer cells to the brain

Cholesterol drugs can effectively alleviate the spread of breast cancer cells to the brain

A new study by the University of Notre Dame in Paris shows that drugs used to treat high cholesterol may interfere with the way breast cancer cells adapt to the brain microenvironment, thereby preventing the spread of cancer to the brain...

2020-10-30
Blocking cellular cholesterol storage may be expected to inhibit the progression of pancreatic cancer

Blocking cellular cholesterol storage may be expected to inhibit the progression of pancreatic cancer

In a research report recently published in the International Journal of Experimental Medicine, scientists from the Cold Spring Harbor Institute and other institutions studied mouse and laboratory-grown pancreatic tissue models to show how cells store...

2020-10-30
\"Good cholesterol\" can be used to predict the risk of heart disease and stroke

\"Good cholesterol\" can be used to predict the risk of heart disease and stroke

High-density lipoprotein (HDL) cholesterol has been called \"good cholesterol\" for decades because it can remove fat and other cholesterol molecules from artery walls...

2020-10-30
Research reveals the effect of cholesterol on cell membranes

Research reveals the effect of cholesterol on cell membranes

For more than a decade, scientists have admitted that cholesterol (an important part of cell membranes) cannot uniformly affect different types of membranes...

2020-10-30
Reveal the mechanism that cholesterol-25-hydroxylase inhibits SARS-CoV-2 and other coronavirus infections

Reveal the mechanism that cholesterol-25-hydroxylase inhibits SARS-CoV-2 and other coronavirus infections

The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant around the world....

2020-10-30
Demystifying the mysterious link between obesity and cancer metastasis

Demystifying the mysterious link between obesity and cancer metastasis

Recently, scientists from Tufts University and other institutions have revealed the relationship between obesity and cancer metastasis through research...

2020-10-29
Scientists have an in-depth understanding of the molecular mechanism of cancer cell resistance to therapies, which may help to develop new personalized anti-cancer therapies!

Scientists have an in-depth understanding of the molecular mechanism of cancer cell resistance to therapies, which may help to develop new personalized anti-cancer therapies!

Scientists from Vanderbilt University and other institutions have identified a special enzyme through research, which may be able to maintain tumor cell growth during cancer drug therapy. The relevant research results may develop new methods for scie...

2020-10-29
How can the body\'s genetic susceptibility be combined with specific environmental factors to induce autoimmune diseases such as multiple sclerosis?

How can the body\'s genetic susceptibility be combined with specific environmental factors to induce autoimmune diseases such as multiple sclerosis?

Scientists from the University of Zurich and other institutions have revealed how this genetic susceptibility (HLA-DR15 gene mutation) can be combined with environmental factors to promote the occurrence of multiple sclerosis, an autoimmune disease i...

2020-10-29
Scientists have identified key target proteins that can effectively treat metabolic diseases such as diabetes and obesity

Scientists have identified key target proteins that can effectively treat metabolic diseases such as diabetes and obesity

A few days ago, in a research report published in the international journal Journal of Biological Chemistry, researchers from Louisiana State University clarified the effect of a protein in the treatment or prevention of metabolic diseases (such as o...

2020-10-29