[Animal Modeling - Efficacy Evaluation] - Age Related Cataract Animal Model

Macaques and humans are both higher animals belonging to the primate order. The anatomy and physiology of their eyes are very similar to those of humans. The normal crystalline lens of macaques is also colorless and transparent, with a biconvex lens ...

2024-08-07

[Animal Modeling Drug Efficacy Evaluation] - Spontaneous Animal Tumor Model

A type of tumor that naturally occurs in experimental animal populations without conscious artificial experimental treatment is called spontaneous tumor...

2024-08-07

[Animal modeling - efficacy evaluation] - transgenic diabetes animal model

Bruning et al. introduced ineffective alleles of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1) into mice through double heterozygosity, resulting in a decrease in IR/IRS-1 expression in the mice...

2024-08-07

[Animal Modeling - Pharmacological Evaluation] - Evaporation induced Mouse Dry Eye Model

Dysfunction of meibomian gland and strong evaporation type rabbit dry eye model. Some special types of mice already have factors of meibomian gland developmental disorders...

2024-08-07

[Animal modeling - efficacy evaluation] - DB/DB obese diabetes mice

Diabetes mice: It was first reported by Hummel et al. (1966) that it was caused by a recessive mutation gene and spontaneously originated from inbred mice (C57BL/Ks) in Jackson\'s laboratory. This gene (db) and obesity (ob) are not alleles, but locat...

2024-08-06

[Animal modeling - Drug efficacy evaluation] - Tooth pulp stimulation induced pain model

rabbits, weighing 1.5-2kg; Drug: Anesthetic; Equipment: dental drill, platinum electrode, linear ramp function stimulator...

2024-08-06

[Animal modeling - Drug efficacy evaluation] - Chronic pain model induced by electrical stimulation of visceral nerves

rabbits, weighing 2-3kg, male or female not limited; Drug: Anesthetic; Instrument: Electrical stimulator...

2024-08-06

[Animal modeling - efficacy evaluation] - poultry hepatitis B virus model

Duck hepatitis B virus (DHBV) was discovered by William et al in 1980, and then it was found in ducks, grey herons and wild geese from different sources...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rabbit Chlamydia Pneumonia Model

Take one month old New Zealand rabbits after birth, first anesthetize them with mild halothane to induce hyperventilation, and then inoculate 1.0ml of pure culture medium containing 1.0 × 10000000-5.0 × 10000000 CFU/ml of Chlamydia pneumoniae from th...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Guinea Pig Pulmonary Tuberculosis Bacterial Model

Female Hartley guinea pigs were used. Mycobacterium tuberculosis in the middle logarithmic growth period was diluted to the required inoculation concentration with sterilized double distilled water. The compartment of the spray was filled with 5ml of...

2024-08-06

【Animal modeling - Drug efficacy evaluation】 - Repeated immunization induced ulcerative colitis in rats

Wistar rats, female, weighing (180 ± 10) g; Medications: pentobarbital, penicillin; Equipment: body locator, electronic stimulator...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Staphylococcus aureus Endometritis Animal Model

Cultivate Staphylococcus aureus ATCC29213 strain and prepare a bacterial suspension of 10000 CFU/ml using physiological saline...

2024-08-06

[Animal modeling - Drug efficacy evaluation]- Establishment of post-traumatic epilepsy animal model by iontophoresis method

Animal: Wistar rats, male, weighing 200-250g; Medication: pentobarbital, FeCl3 solution; Instruments: rat stereotaxic apparatus, wireless Bluetooth EEG monitoring system, high-speed dental drill, tooth holder powder, 1 PVC thin tube with an inner dia...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rat Pseudomonas aeruginosa Pneumonia Model

Secretory Pseudomonas aeruginosa PAO1 strain and its variant PAOR strain were cultured overnight in tryptone soy broth at 37 ° C. After centrifugation, they were suspended in PBS (pH 7.4), washed by centrifugation, and the precipitate was suspended i...

2024-08-06

[[Animal modeling - efficacy evaluation] - primary diabetes BB rats

BB Wistar rat is a spontaneous diabetes animal model...

2024-08-06

[Animal Modeling - Efficacy Evaluation] - Mongolian Sand Rat Helicobacter pylori Model

5-week-old male Mongolian sand rats without specific pathogen grade were fed standard feed and sterilized water with libitum...

2024-08-06