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How to prepare animal model of enterohemorrhagic Escherichia coli?

How to prepare animal model of enterohemorrhagic Escherichia coli?

The typical strain of Enterohemorrhagic E.coli (EHEC) is EHEC O157:H7. Infection with this bacteria can cause diarrhea, hemorrhagic colitis (HC), and hemolytic uremia. Syndrome (haemolytic uraemic syndrome, HuS) and thrombotic thrombocytopenic purpur...

2020-08-12
How to prepare a rat model of Parkinson\'s disease caused by rotenone?

How to prepare a rat model of Parkinson\'s disease caused by rotenone?

Through Nissl staining, it can be seen under the microscope that the number of neurons in the substantia nigra of the model group is reduced, and the surviving neurons shrink and are accompanied by gliosis....

2020-08-12
How to prepare nude mouse models of Candida albicans and Cryptococcus neoformans infection?

How to prepare nude mouse models of Candida albicans and Cryptococcus neoformans infection?

In the replication method, nude mice were used to conduct infection experiments on Candida albicans, Cryptococcus neoformans, squirrel histoplasma and dermatophytes, and transplanted to the skin of psoriasis patients to observe the cause...

2020-08-12
How to prepare an animal model of Candida albicans infection with vaginitis?

How to prepare an animal model of Candida albicans infection with vaginitis?

Candida albicans vaginitis is a fungal infection of the vaginal mucosa, which is very common in women of childbearing age. Clinically, 85% to 95% of externally negative vaginas are caused by Candida albicans...

2020-08-12
How to prepare mouse acute myocardial infarction animal model?

How to prepare mouse acute myocardial infarction animal model?

Touch the intercostal space where the apex of the rat is most pulsating, cut the skin and intercostal muscles, squeeze out the heart, find the anterior descending branch at the junction of the pulmonary artery cone and the left atrial appendage, liga...

2020-08-12
How to prepare a transgenic animal model of Epstein-Barr virus (EBV)?

How to prepare a transgenic animal model of Epstein-Barr virus (EBV)?

Latent membrane protein (LMP): including LMP-1, 2A, 28. LMP-1 gene is currently the only confirmed EB virus malignant transformation gene. EBV-related animal models There are not many EBV-related animal models established so far, and they mainly focu...

2020-08-12
How to prepare an animal model of chronic myocardial ischemia?

How to prepare an animal model of chronic myocardial ischemia?

Use specially bred small pigs for experimental use. For chronic experiments, it is best to choose piglets weighing 25-30kg and about 6 months old to ensure the convenience of the operation and the weight increase at the end of the study....

2020-08-12
How to prepare animal models of infectious diseases?

How to prepare animal models of infectious diseases?

The selection and preparation of animals is the key to the success of the model preparation. For mature pathogenic animal models, the type of animal and the level of microorganisms have been clarified and should be prepared strictly in accordance wit...

2020-08-12
How to prepare animal model of myocardial infarction caused by plaque rupture?

How to prepare animal model of myocardial infarction caused by plaque rupture?

The rupture of atherosclerotic plaques in the coronary arteries and the accompanying arterial thrombosis is the final end point of the long and complicated pathophysiological process of atherosclerosis, which is difficult to perform in humans in any ...

2020-08-12
How to prepare L cell line megaloblastic anemia mouse model? -【Animal experiment】

How to prepare L cell line megaloblastic anemia mouse model? -【Animal experiment】

Temperature-sensitive L cell mutant mouse model: Thompson (1971) isolated two temperature-sensitive mouse mutant L cells tsA1S9 and tsC1. Cytological studies have shown that these two ts cell mutations are responsible for similar morphological change...

2020-08-12
How to prepare a model of myocardial infarction caused by vascular mechanical occlusion?

How to prepare a model of myocardial infarction caused by vascular mechanical occlusion?

  In previous studies, models of myocardial infarction have been established in various experimental animals. When small animals can be selected according to the requirements of the research, mice are the best choice. On the one hand, the cost of buy...

2020-08-12
How to prepare an animal model of hereditary hypochromic anemia?

How to prepare an animal model of hereditary hypochromic anemia?

Sex-related hereditary anemia mice, the gene symbol sla is a recessive recessive related to the sex of the X chromosome...

2020-08-12
How to prepare dengue fever virus transgenic animal model?

How to prepare dengue fever virus transgenic animal model?

The replication method mainly uses gene knockout to create animal models...

2020-08-12
How to prepare related animal models of chronic myocardial ischemia?

How to prepare related animal models of chronic myocardial ischemia?

Therapeutic angiogenesis has become one of the hotspots of coronary heart disease research since the 1990s...

2020-08-12
Mouse model of renal tubular necrosis-【animal model】

Mouse model of renal tubular necrosis-【animal model】

BALB/c mice, placed in an environment containing 5 mg of chloroform per liter of air, for 3 hours, can cause kidney necrosis in varying degrees...

2020-08-12
How to establish a rabbit restenosis model? -【Animal experiment】

How to establish a rabbit restenosis model? -【Animal experiment】

Animal selection Choose healthy Japanese white rabbits or New Zealand rabbits, both male and female...

2020-08-12