【Animal modeling】-Application of three mouse enterovirus nucleic acid detection technologies in mouse health monitoring

To use nucleic acid detection technology to detect MHV, Reo-3 and MNV enteroviruses in cecal contents of mice, and to compare the results with serological detection results to analyze the applicability of nucleic acid detection in mouse health monito...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - Stimulation of vagus nerve AF model

The excitation of the vagus nerve can significantly shorten AERP, while also increasing the dispersion of AERP, providing opportunities for multi wavelet reentry, leading to the susceptibility and stability of AF...

2024-07-23

[Animal Modeling - Efficacy Evaluation]- Transgenic Animal Model for Tumor Angiogenesis

There are many reports on transgenic animal models of tumor angiogenesis...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - Rabbit Congestive Heart Failure Model

New Zealand white rabbit, 16-20 weeks old, male, weighing 2.1-3.3kg; Medications: Su Mian Xin, Penicillin, Ketamine/Diazepam; Instrument: BL-420 Biological Function Experiment System...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - Cyanosis type Heart Disease Animal Model

New Zealand white rabbit, male, 5-6 months old, weighing 1.5-2.0kg; Drug: Sodium thiopental...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - High Fat Feed Induced Chicken Hyperlipidemia Animal Model

Lecheng chicken, 4-8 weeks old, male or female not limited; Medication: High fat feed...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - Rabbit Oleic Acid Type Acute Lung Injury Model

Healthy rabbits, male or female, weighing 2.0-2.5kg; Medications: Oleic acid, pentobarbital, heparin physiological saline...

2024-07-23

[Animal Modeling Drug Efficacy Evaluation] - Elderly Mouse Acute Lung Injury Model

24 month old Wistar rats, male or female, weighing (456.5 ± 38.1) g; Medications: oleic acid, lipopolysaccharide O111:B4, ketamine...

2024-07-23

[Animal Modeling - Efficacy Evaluation] - Rabbit Perfluoroisobutylene Inhalation Acute Lung Injury Model

Healthy female New Zealand white rabbit, weighing (3.5 ± 0.4) kg; Drug: Perfluoroisobutylene (PFIB) with a purity of 98%, ethyl carbamate, physiological saline, heparin, potassium permanganate solution; Equipment: Air compression pump, microinjection...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - Rat Pulmonary Oxidative Injury Model

3-month-old male SD rats; Equipment: O3 generator, dynamic poisoning box...

2024-07-23

[Animal Modeling - Pharmacological Evaluation] - Acute Lung Injury Model in Abdominal Infection Rats

SD rats, male or female, weighing 250-350g; Drug: Ketamine hydrochloride; Instruments: syringes, surgical instruments...

2024-07-23

[Animal Modeling] Drug Efficacy Evaluation Induced Psoriasis Animal Model

Propranolol application induced ear psoriasis model in guinea pigs. This model is commonly used in China. Huang et al. applied 5% propranolol to the ear of guinea pigs (350-400g) and the ear of guinea pigs (0.3g per 1cm2 of drug) twice a day for two...

2024-07-22

[Animal Modeling] Drug Efficacy Evaluation Reflux Gastritis Model

Male rats weighing 200-250g; Medications: Pentobarbital, physiological saline, iodine...

2024-07-22

[Animal Modeling - Pharmacological Evaluation] - Animal Model of Spleen Qi Deficiency Syndrome Caused by Bitter Cold Diarrhea (Rhubarb)

Adult mice were orally administered with a dose of 0.2ml/10g body weight of raw rhubarb solution (1g of raw medicine per milliliter) twice a day for 7 consecutive days. Observe changes in mouse food intake, stool, activity, fur, body weight, etc. Aft...

2024-07-22

[Animal modeling - Drug efficacy evaluation] - Dry knot constipation model

Healthy Kunming mice, weighing (30 ± 2) g, both male and female...

2024-07-22

【Animal Modeling - Pharmacological Evaluation 】- Oxazolidone Colitis Mouse Model

BALB/c mice, 7-8 weeks old, weighing 25-30g; Medications: Oxazolidone, Metoclopramide, Ethanol...

2024-07-22