Based on JAK2/STAT3/SOCS3 signal pathway to explore the effect of compound glycyrrhizin on experimental autoimmune encephalomyelitis

To explore the preventive and therapeutic effects of compound glycyrrhizin (CG) on experimental autoimmune encephalomyelitis (EAE) mice and its influence on JAK2 / STAT3 / SOCS3 signal pathway...

2020-12-18

The host\'s unbalanced response to SARS-CoV-2 promotes the development of COVID-19

After the virus replicates, the physiological response to the virus infection usually begins at the cellular level. After the virus enters, the infected cells through any of the multiple pattern recognition receptors (PRR) will detect the replication...

2020-12-18

Effect of betulin on oxidative stress and apoptosis of PC12 cells induced by Aβ25-35

To investigate the effect of betulin on oxidative stress and apoptosis of PC12 cells induced by Aβ25-35...

2020-12-18

Astragalus Notoginseng Mixture Improves Renal Inflammation in Mice with Diabetic Nephropathy by Regulating Arid2-IR/NF-κB Signal Axis

To study the therapeutic effect of Huangqi Sanqi Mixture on diabetic nephropathy (DN) mice and explore the underlying regulatory mechanism...

2020-12-18

Observation of the ultrastructure of Fufangjianerji against senile cochlear nerve cell apoptosis and up-regulating the expression of NeuN and BDNF

Using transmission electron microscope to observe the effect of traditional Chinese medicine compound ear-invigorating agent on the apoptosis of outer hair cell (OHC) and spiral ganglion neurons (SGN) of senile cochlea in mice...

2020-12-18

Study on the protective effect of DHA on weight gain induced by high-fat food

To explore the mechanism by which DHA inhibits fat gain induced by high-fat foods...

2020-12-18

Analysis of candidate genes related to the role of PD-L1 in tuberculosis infection using Pdl1 knockout macrophage transcription profile

Analyze the changes in the transcription profile of macrophages (MΦ) specifically knocked out by the programmed death ligand 1 (Pdl1) infected by tuberculosis (Mtb), and screen the candidate genes related to the action of PD-L1 in MΦ...

2020-12-18

SARS-CoV-2 is susceptible to infecting human iPSC-derived cardiomyocytes

COVID-19 is a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

2020-12-18

Rhesus monkey experiments show that new antibodies may lead to new treatments for AIDS

An international research team published a paper in the \"Science\" magazine, claiming that the combination of \"α4β7\" antibody injection and antiretroviral drugs may become a new treatment for HIV infection...

2020-12-18

Diabetes \"star\" drug mechanism of action cracked

People with diabetes must be no strangers to “metformin”, which is currently the “star” drug for the treatment of diabetes worldwide...

2020-12-18

DNA vaccine successfully prevents rhesus monkeys from being infected with Zika virus

Researchers from the American Institute of Allergy and Infectious Diseases published a paper in the \"Science\" magazine saying that they have developed a new DNA (deoxyribonucleic acid) Zika vaccine. Animal experiments have shown that this...

2020-12-18

Progress in the genomics research of bacterial drug resistance in the Chinese Academy of Sciences

The latest progress of Zhu Baoli\'s research group in the genomics research of bacterial resistance of the Institute of Microbiology, Chinese Academy of Sciences. The research is based on the big data of genomics for the first time. The evolution of ...

2020-12-18

New tumor analysis method can identify high-risk prostate cancer

The genetic pathway of cancer cells indicates that the patient’s tumor disease may develop into an aggressive disease...

2020-12-18

New \"Trojan Horse\" antibody can restrain Ebola virus infection

The top international academic journal \"Science\" published a research paper online by researcher Kartik Chandran of Einstein College of Medicine. The study proved that a two-pronged antibody can counter a unique immune escape mechanism, s...

2020-12-18

New ways to treat heart disease and cancer

Recently, an article published in the Proceedings of the National Academy of Sciences of the United States pointed out that combining ultrasound energy and ultrasound microbubbles to perforate cells may become a new tool in the fight against cardiova...

2020-12-18

Shark fins and meat contain large amounts of neurotoxins related to Alzheimer\'s

Recent studies have shown that BMAA is associated with neurodegenerative diseases such as Alzheimer\'s disease and amyotrophic lateral sclerosis (ALS)...

2020-12-18