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[Animal Modeling Drug Efficacy Evaluation] - Small Pig Alcoholic Fatty Liver Model

[Animal Modeling Drug Efficacy Evaluation] - Small Pig Alcoholic Fatty Liver Model

Animal models of alcoholic fatty liver are divided into two categories: acute alcoholic fatty liver models and chronic alcoholic fatty liver models...

2024-07-16
[Animal Modeling - Efficacy Evaluation] - Sodium Selenate Cataract Animal Model

[Animal Modeling - Efficacy Evaluation] - Sodium Selenate Cataract Animal Model

  After reaching the eye tissue lens through fluid circulation, selenite oxidizes the thiol groups of proteins, leading to the inhibition of Ca2+- ATPase. This causes a large accumulation of Ca2+- ATPase in the lens nucleus fibers, leading to the act...

2024-07-16
Animal Modeling Drug Efficacy Evaluation Induced Nasopharyngeal Carcinoma Animal Model

Animal Modeling Drug Efficacy Evaluation Induced Nasopharyngeal Carcinoma Animal Model

The induced nasopharyngeal carcinoma model is mainly a nasopharyngeal carcinoma animal model formed by the action of chemical carcinogens on animals...

2024-07-16
【Animal Modeling - Pharmacological Evaluation】 - Acute Myeloid Leukemia Animal Model

【Animal Modeling - Pharmacological Evaluation】 - Acute Myeloid Leukemia Animal Model

The human acute myeloid leukemia cell line HL-60 was allogeneic and transplanted into SCID mice with T and B lymphocyte function combined with immune deficiency to establish a SCID mouse model with human hematopoietic function. This is currently the ...

2024-07-16
【Animal Modeling】-Research on Animal Model of Renal Vascular Hypertension

【Animal Modeling】-Research on Animal Model of Renal Vascular Hypertension

Renal vascular hypertension is the stenosis or obstruction of the main trunk or branches of the renal arteries on one or both sides, which reduces the flow of renal blood vessels and leads to hypertension caused by renal ischemia. It is the most comm...

2024-07-15
【Animal Modeling】-Cloning and Molecular Characterization of the Full-length Coding Sequence of Tree Shrews HGF

【Animal Modeling】-Cloning and Molecular Characterization of the Full-length Coding Sequence of Tree Shrews HGF

To obtain the full-length coding sequence of tree shrew hepatocyte growth factor and analyze its molecular characteristics...

2024-07-12
【Animal Modeling】-What is the method of extracting rat cerebrospinal fluid?

【Animal Modeling】-What is the method of extracting rat cerebrospinal fluid?

Improve the method of extracting rat cerebrospinal fluid based on the negative pressure suction device method, and increase the success rate of rat cerebrospinal fluid collection?...

2024-07-10
【Animal modeling】-Effect of vitamin D deficiency on the pathogenesis of spontaneously diabetic rats

【Animal modeling】-Effect of vitamin D deficiency on the pathogenesis of spontaneously diabetic rats

To investigate the effect of vitamin D (VD) deficiency on the pathogenesis of spontaneous diabetic rats...

2024-07-10
[Animal modeling] - Establishment and comparison of in situ model of pancreatic cancer in mice suitable for minimally invasive ablation therapy

[Animal modeling] - Establishment and comparison of in situ model of pancreatic cancer in mice suitable for minimally invasive ablation therapy

To explore the advantages and disadvantages of establishing an in situ model of pancreatic cancer in mice by tumor cell injection and tumor tissue transplantation, and to provide a technical reference for establishing an in situ model of pancreatic c...

2024-07-10
[Animal modeling] - Effect of silencing heme oxygenase-1 on the mouse model of acute monocytic leukemia

[Animal modeling] - Effect of silencing heme oxygenase-1 on the mouse model of acute monocytic leukemia

To investigate the effect of silencing the expression of heme oxygenase-1 (HO-1) on leukemic disease in mice with acute monocytic leukemia...

2024-07-10
【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...

2024-07-10
[Animal Modeling Pharmacodynamic Evaluation]- Mouse Chlamydia Pneumonia Model

[Animal Modeling Pharmacodynamic Evaluation]- Mouse Chlamydia Pneumonia Model

The CWL-029 strain of Chlamydia pneumoniae was propagated in HEp-2 cell culture medium. Infected cells were collected using sterile glass beads, destroyed by ultrasound, and purified by centrifugation at low and high speeds for one cycle. They were s...

2024-07-09
[Animal Modeling Pharmacodynamic Evaluation ]- Rat Pneumocystis Pneumocystis Pneumonia Model

[Animal Modeling Pharmacodynamic Evaluation ]- Rat Pneumocystis Pneumocystis Pneumonia Model

  Model animals are fed with pellet feed in cages. After observing for one week without any abnormalities, subcutaneous injection of cortisone acetate, 25mg/time, twice a week. At the same time, add tetracycline (100mg/100ml) to drinking water to pre...

2024-07-09
[Animal Modeling - Pharmacodynamic Evaluation] - Small Pig Root Absorption Model

[Animal Modeling - Pharmacodynamic Evaluation] - Small Pig Root Absorption Model

Root resorption is a common and difficult to treat complication in orthodontic treatment, and there are many related factors that can cause root resorption, including age, gender, nutritional status, type of orthodontic device, orthodontic force, ort...

2024-07-08
[Animal Modeling - Pharmacodynamic Evaluation] - Repair of Bone Defects Around Small Pig Implants

[Animal Modeling - Pharmacodynamic Evaluation] - Repair of Bone Defects Around Small Pig Implants

Implant restoration has been increasingly widely used in clinical practice, but the loss of teeth due to trauma, tumors, periodontal disease and other reasons often leads to excessive absorption of alveolar bone, resulting in insufficient bone mass a...

2024-07-08
[Animal modeling - Pharmacodynamic evaluation] - Small pig pulpitis model

[Animal modeling - Pharmacodynamic evaluation] - Small pig pulpitis model

Five Chinese experimental miniature pigs weighing 14-26kg were used, with three males and two females. Select the first permanent molars of the upper and lower jaw, and create a pulpitis model with bilateral mandibular lateral incisors. After injecti...

2024-07-08